Minidiab Tablets 5Mg (1 Strip = 10 Tablets)

Name: Minidiab Tablets 5Mg (1 Strip = 10 Tablets)
Brand: PFIZER LABORATORIES
Price: 27.80

Brand : pfizer laboratories

Rs. 27.80

Rs. 29.30

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Minidiab Tablets Specification

Requires Prescription (YES/NO)

Yes

Generics

Glipizide

Used For

Diabetes

How it works

Glipizide is an oral blood -glucose -lowering drug of the sulfonylurea class. The primary mode of action of glipizide is the stimulation of insulin secretion from the beta-cells of pancreatic islet tissue. Stimulation of insulin secretion by glipizide in response to a meal is of major importance. Fasting insulin levels are not elevated even on long-term glipizide administration, but the post-prandial insulin response continues to be enhanced after at least 6 months of treatment. The insulinotropic response to a meal occurs within 30 minutes after oral dose of glipizide in diabetic patients, but elevated insulin levels do not persist beyond the time of the meal challenge. There is also increasing evidence that extrapancreatic effects involving potentiation of insulin action form a significant component of the activity of glipizide.

Minidiab Tablets Usage And Safety

Dosage

Glipizide

Side Effects

Hypoglycaemia (not enough sugar in the blood) , feeling sick (nausea) , diarrhoea , pain in the stomach , drowsiness , shakiness (tremor) , blurred vision , being sick (vomiting) , jaundice (yellowing of the skin and eyes, itching and dark urine) eczema (inflammation of skin) .

Drug Interactions

• Miconazole, fluconazole or voriconazole • Non-steroidal anti-inflammatory agents • Aspirin or aspirin like medicines known as salicylates • Beta-blockers • Angiotensin converting enzyme (ACE) inhibitors • Cimetidine • Sulfonamides or chloramphenicol • Quinolones • Monoamine oxidase inhibitors • Probenecid • Coumarin anticoagulants • Fibrates Danazol (a hormone treatment). • Chlorpromazine, thioridazine).• Corticosteroids (e.g. prednisolone) • Sympathomimetic agents (e.g. salbutamol, isoprenaline) • Hormonal agents • Thiazides or other diuretics (water tablets e.g. bendroflumethiazide) • Thyroid products • Phenytoin • Nicotinic acid • Calcium channel blocking agents e.g. nifedepine or verapamil). • Isoniazid .

Indication

It is used to treat diabetes (Type II, non-insulin-dependent diabetes) and helps to lower your blood glucose (sugar) levels, when a change in diet alone is not enough to control the condition.

When not to Use

Do not take Glipizide: • If you are allergic to glipizide, similar antidiabetic medicines or any of the other ingredients of this medicine • If you have insulin-dependent diabetes (also called juvenile or Type I diabetes) which would have probably started in your childhood. • If you have ketone bodies and sugar in your urine (this may mean you may have diabetic ketoacidosis). • If you suffer from episodes of unconsciousness (this may mean you may have diabetic coma) .

Minidiab Tablets Precautions

Precaution

All sulfonylurea agents are capable of producing severe hypoglycaemia. Renal or hepatic insufficiency may cause elevated blood levels of glipizide and the latter may also diminish gluconeogenic capacity, both of which increase the risk of serious hypoglycaemic reactions. Elderly, debilitated or malnourished patients and those with adrenal or pituitary insufficiency are particularly susceptible to the hypoglycaemic action of glucose-lowering drugs.

Minidiab Tablets Warnings

Warning 1

Since glipizide belongs to the class of sulfonylurea agents, caution should be used in patients with G6PD deficiency. Treatment of patients with G6PD deficiency with sulfonylurea agents can lead to haemolytic anaemia and a non-sulfonylurea alternative should be considered.

Warning 2

When a patient stabilised on a diabetic regimen is exposed to stress such as fever, trauma, infection, or surgery, a loss of control may occur. At such times, it may be necessary to discontinue glipizide and administer insulin.

Warning 3

Patients should be informed of the potential risks and advantages of glipizide and of alternative modes of therapy. They should also be informed about the importance of adherence to dietary instructions, of a regular exercise program, and of regular testing of urine and/or blood glucose.

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