Acefer -Fchew 10 Tablets

Brand : saffron pharmaceutical comp

Rs. 209.00

Rs. 220.00

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SPECIFICATION

Requires Prescription (YES/NO)

Yes

Generics

Folic Acid , Iron Hydroxide Poly Maltose Complex

Used For

Anaemia

How it works

In order to be bound to transferrin and ferritin, iron supplements must necessarily be in a Fe+3) level of oxidation. Iron is transported to the bone marrow as ferric ion (Fe+3) bound to transferrin and is reduced to theferrous form (Fe+2) for its release in the erythroid progenitor cells and is finally transferred to the protoporphyrin for the synthesis of hemoglobin.Folic acid is required for nucleoprotein synthesis and maintenance of normal erythropoiesis; precursor of tetrahydrofolic acid, which is necessary for transformylation reactions in the biosynthesis of purines and thymidylates of nucleic acids.

USAGE AND SAFETY

Dosage

Folic Acid , Iron Hydroxide Poly Maltose Complex

Side Effects

The side effects reported are occasional gastrointestinal irritation such as sensation of repletion, epigastric pain, nausea, constipation and diarrhea. There may be a dark coloration or black stools which is of no clinical significance. It does not cause teeth staining.

Drug Interactions

Phenytoin , Sulfasalazine.

Indication

Iron (III)-hydroxide polymaltose complex + Folic acid are indicated for: - The treatment of latent iron deficiency. - Manifest iron deficiency. - Prophylactic therapy of iron and folic acid deficiency before during and after pregnancy (during lactation).

When not to Use

Iron (III)-hydroxide polymaltose complex + Folic acid are contraindicated in patients:- Who show hypersensitivity to iron.- Receiving repeated blood transfusions.- With iron overload (e.g. hemochromatosis, hemosiderosis).- Who have disturbances in iron utilization (e.g. thalassemia, sidero-achrestic anemia, lead anemia).- Who have anemia not caused by iron deficiency (e.g. hemolytic anemia or megaloblastic anaemia caused by vitamin B12 deficiency)

PRECAUTIONS

Precaution

In cases of anemia due to infections or malignancy, the substituted iron is stored in the reticulo-endithelial system, from which it is mobilized and utilized only after curing the primary disease.

WARNINGS

Warning 1

Since the iron is complex bound, ionic interactions with food components (phytin, oxalates, tannin etc.) and concomitant administration of drugs (tetracyclines, antacids) are unlikely to occur.

Warning 2

During pregnancy and lactation Iron (III)-hydroxide polymaltose complex + Folic acid should be used only if clearly required after consultation with the physician.

Warning 3

In case of overdosage, initially epigastric pain, diarrhea and vomiting can occur and may include metabolic acidosis, convulsions and coma after apparent recovery.