Bremax Tablets 1Mg (1 Strip = 10 Tablets)
Brand : abbot laboratories (pak) ltd
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Bremax Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Tulobuterol
Used For
Asthma
How it works
The primary pharmacological action of beta-adrenergic drugs is to stimulate adenyl cyclase, the enzyme which catalyzes the formation of cyclic-3',5' adenosine monophosphate (cyclic AMP) from adenosine triphosphate (ATP). The cyclic AMP thus formed mediates the cellular response that results in bronchodilation. Tulobuterol, due to its highly selective action on beta-2 adrenoceptors, relaxes the bronchial smooth muscle and has been shown to be clinically successful in the symptomatic treatment of reversible obstructive airways disease (ROAD) such as bronchial asthma, and also in bronchitis and emphysema.
Bremax Tablets Usage And Safety
Dosage
Tulobuterol
Side Effects
Hypertension, palpitations, angina, tachycardia, vomiting, vertigo, central nervous system stimulation, insomnia and headache .
Drug Interactions
Systemic sympathomimetics , beta blocking agents.
Indication
Tulobuterol is indicated for prophylaxis and control of bronchospasm in bronchial asthma, chronic bronchitis, asthmatic bronchitis, pulmonary emphysema, bronchiectasis, tracheobronchitis with emphysema and other bronchospastic disorders and conditions characterized by bronchoconstriction .
When not to Use
Administration of tulobuterol is contraindicated in patients with known hypersensitivity to sympathomimetic amines or any of the formulation components .
Bremax Tablets Precautions
Precaution
Long-Acting Beta Agonists should only be used long-term in patients whose asthma cannot be adequately controlled on asthma controller medications alone. Tulobuterol should be used with caution in patients with diabetes mellitus, hypertension, hyperthyroidism, and seizure disorders. Caution should be observed in patients with renal failure in view of the kidney being the principle route of elimination of the drug. Dosage may also require individualization in patients with impaired liver function as normally tulobuterol is extensively metabolized by the liver.
Bremax Tablets Warnings
Warning 1
As with other sympathomimetic bronchodilator agents, tulobuterol should be administered cautiously to cardiac patients, especially those with associated arrhythmias, coronary insufficiency, or myocardial ischemia.
Warning 2
Clinical trials to study the effects of tulobuterol in combination treatment with theophylline or aerosol corticosteroids failed to demonstrate any deleterious effects. The concomitant systemic use of tulobuterol with other systemic sympathomimetic agents is not recommended, since their combined effect on the cardiovascular system may be deleterious to the patient.
Warning 3
Tulobuterol should not be prescribed together with beta-blocking agents. Although an intravenous injection of a cardio-selective beta-blocking agent can be given as a specific antidote for tulobuterol overdosage, these agents should be used with caution in patients with bronchospasm.
Bremax Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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