Calan Tablets 80Mg

Brand : searle pakistan (pvt) ltd.

Rs. 206.50

Rs. 217.23

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SPECIFICATION

Requires Prescription (YES/NO)

Yes

Generics

Verapamil Hydrochloride

Used For

Hypertension

How it works

Verapamil is in a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart and slows electrical activity in the heart to control the heart rate.

USAGE AND SAFETY

Dosage

Verapamil Hydrochloride

Side Effects

Constipation , Dyspnea , Dizziness , Bradycardia , Nausea , Hypotension , AV block , Headache , Edema , CHF, Rash , Edema , Flushing , Fatigue , angina pectoris, atrioventricular dissociation, chest pain, claudication,myocardial infarction, palpitations, purpura (vasculitis), syncope, diarrhea, dry mouth, gastrointestinal distress, gingival hyperplasia , blurred vision, tinnitus.

Drug Interactions

HMG-CoA reductase inhibitors , Ivabradine , Beta-blockers , Digitalis , Disopyramide , Flecainide , Quinidine , Alcohol , Nitrates , Cimetidine , Lithium , Carbamazepine , Rifampin , Phenobarbital , Cyclosporin , Theophylline , Telithromycin , Clonidine.

Indication

It is indicated for the treatment of hypertension.

When not to Use

Verapamil HCl is contraindicated in:1. Severe left ventricular dysfunction 2. Hypotension (systolic pressure less than 90 mm Hg) or cardiogenic shock 3. Sick sinus syndrome (except in patients with functioning artificial ventricular pacemaker).

PRECAUTIONS

Precaution

Since verapamil is highly metabolized by the liver, it should be administered cautiously to patients with impaired hepatic function.

WARNINGS

Warning 1

Occasionally, the pharmacologic action of verapamil may produce a decrease in blood pressure below normal levels, which may result in dizziness or symptomatic hypotension.

Warning 2

Verapamil has a negative inotropic effect, which in most patients is compensated by its afterload reduction (decreased systemic vascular resistance) properties without a net impairment of ventricular performance.

Warning 3

Elevations of transaminases with and without concomitant elevations in alkaline phosphatase and bilirubin have been reported.