
SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Cephalexin
Used For
Bacterial Infection
How it works
Cephalexin is an oral broad-spectrum antibiotic. In adequate concentrations it is bactericidal for sensitive proliferating microorganisms by inhibiting the biosynthesis of the cell wall.
USAGE AND SAFETY
Dosage
Cephalexin
Side Effects
Nausea, vomiting, diarrhoea and abdominal discomfort , Dyspepsia , Transient hepatitis and cholestatic jaundice , rash, urticaria, angioedema and rarely erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis (exanthematic necrolysis) , genital and anal pruritus, genital candidiasis, vaginitis and vaginal discharge, dizziness, fatigue, headache, agitation, confusion, hallucinations, arthralgia, arthritis and joint disorders, Eosinophilia, neutropenia, thrombocytopenia, haemolytic anaemia and slight elevations in AST and ALT.
Drug Interactions
Bacteriostatic antibiotics , Uricosuric drugs (e.g. probenecid) , Metformin , ethacrynic acid, furosemide , aminoglycosides, polymyxin, colistin , Oral anticoagulants , Typhoid vaccine , Oral contraceptives , Cytotoxic drugs .
Indication
It is indicated for treatment of respiratory tract infections (RTIs), urinary tract infections (UTIs), skin and soft tissue infections, otitis media and other infections due to sensitive organisms.
When not to Use
Cephalexin is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Severe systemic infections, which require parenteral cephalosporin treatment, should not be treated orally during the acute stage.
PRECAUTIONS
Precaution
Cephalosporins should be given with caution to penicillin-sensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and cephalosporins. Patients have had severe reactions (including anaphylaxis) to both drugs.
WARNINGS
Warning 1
Prolonged use of cephalexin may result in the overgrowth of non-susceptible organisms. Careful observation of the patient is essential. If superinfection occurs during therapy, appropriate measures should be taken.
Warning 2
Cephalexin should be administered with caution in the presence of markedly impaired renal function as it is excreted mainly by the kidneys. Careful clinical and laboratory studies should be made because the safe dosage may be lower than that usually recommended.
Warning 3
Cephalexin is excreted in human milk in low concentrations and should be used with caution in nursing mothers.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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