Cordion Dobutmin Injection Iv 250Mg/5Ml

Name: Cordion Dobutmin Injection Iv 250Mg/5Ml
Brand: SIZA INTERNATIONAL
Price: 332.5

Brand : siza international

Rs. 332.50

Rs. 350.00

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Cordion Dobutmin Specification

Requires Prescription (YES/NO)

Yes

Generics

Dobutamine

Used For

Arrhythmia

How it works

The onset of action of dobutamine is within 1 to 2 minutes; however, as much as 10 minutes may be required to obtain the peak effect of a particular infusion rate. The plasma half-life of dobutamine hydrochloride in humans is 2 minutes. The principal routes of metabolism are methylation of the catechol and conjugation. In human urine, the major excretion products are the conjugates of dobutamine and 3-O-methyl dobutamine. The 3-O-methyl derivative of dobutamine is inactive.

Cordion Dobutmin Usage And Safety

Dosage

Dobutamine

Side Effects

Increased Heart Rate, Blood Pressure, nausea, headache, anginal pain, nonspecific chest pain, palpitations, and shortness of breath. Isolated cases of thrombocytopenia have been reported.

Drug Interactions

General anesthetics , bretylium , beta-blockers (non-selective ones) , guanethidine , MAO inhibitors, methyldopa , reserpine , TCAs , beta-adrenergic blockers .

Indication

Dobutamine Injection, USP is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.In patients who have atrial fibrillation with rapid ventricular response, a digitalis preparation should be used prior to institution of therapy with dobutamine hydrochloride.

When not to Use

Dobutamine hydrochloride is contraindicated in patients with idiopathic hypertrophic subaortic stenosis and in patients who have shown previous manifestations of hypersensitivity to Dobutamine Injection, USP solution.

Cordion Dobutmin Precautions

Precaution

During the administration of Dobutamine Injection, USP, as with any adrenergic agent, ECG and blood pressure should be continuously monitored. In addition, pulmonary wedge pressure and cardiac output should be monitored whenever possible to aid in the safe and effective infusion of dobutamine hydrochloride. Hypovolemia should be corrected with suitable volume expanders before treatment with dobutamine hydrochloride is instituted.

Cordion Dobutmin Warnings

Warning 1

Dobutamine hydrochloride may cause a marked increase in heart rate or blood pressure, especially systolic pressure. Approximately 10% of patients in clinical studies have had rate increases of 30 beats/minute or more, and about 7.5% have had a 50 mm Hg or greater increase in systolic pressure. Usually, reduction of dosage promptly reverses these effects. Because dobutamine hydrochloride facilitates atrioventricular conduction, patients with atrial fibrillation are at risk of developing rapid ventricular response. Patients with pre-existing hypertension appear to face an increased risk of developing an exaggerated pressor response.

Warning 2

Dobutamine hydrochloride may precipitate or exacerbate ventricular ectopic activity, but it rarely has caused ventricular tachycardia.

Warning 3

Reactions suggestive of hypersensitivity associated with administration of Dobutamine Injection, USP, including skin rash, fever, eosinophilia, and bronchospasm, have been reported occasionally.

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