Epigran Iv Injection 250Mg/5Ml
Brand : atco laboratories limited
Requires Prescription (YES/NO)
How it works
Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. This blocks sustained high frequency repetitive firing of action potentials.
USAGE AND SAFETY
Bruising, fever , Skin rash, fever, swollen glands, increase in a type of white blood cell (eosinophilia), and inflammation of internal organs (liver, lungs, heart, kidneys and large intestine), Sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, rash or itching (especially affecting the whole body). There is a higher incidence of this in black patients. If you develop potentially life-threatening skin rashes that causes blistering (this can affect the mouth and tongue). These may be signs of a condition known as Stevens Johnson Syndrome, or toxic epidermal necrolysis (TEN). These have been reported very rarely.
Medicines used for heart and circulation problems (e.g. dicoumarol, amiodarone, reserpine, digitoxin, digoxin, mexiletine, nisoldipine, furosemide, quinidine, warfarin and calcium channel blockers including diltiazem and nifedipine) - Medicines used for epilepsy (e.g. carbamazepine, lamotrigine, phenobarbital, sodium valproate, valproic acid, oxcarbazepine, topiramate, succinimides including ethosuximide, and vigabatrin) - Medicines used to treat fungal infections (e.g. amphotericin B, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, miconazole) - Medicines used for tuberculosis and other infections (e.g. chloramphenicol, isoniazid, rifampicin, sulfonamides, sulfadiazine, sulfamethizole, sulfamethoxazole-trimethoprim, sulfaphenazole, sulfisoxazole, doxycycline, ciprofloxacin) - Medicines used for stomach ulcers (e.g. omeprazole, sucralfate and the medicines known as H2 antagonists including cimetidine, ranitidine, famotidine and some antacids) - Medicines used for asthma and bronchitis (e.g. theophylline) - Medicines used for pain and inflammation (e.g. phenylbutazone, propoxyphene, salicylates including aspirin and steroids) .
Oral : Epilepsy particularly of the grand mal type and psychomotor seizures . Migraine & trigeminal neuralgia . Inj : Status epilepticus , seizures in neurosurgery .
When not to Use
Do not take Phenytoin If you are allergic (hypersensitive) to phenytoin, or any of the other ingredients of this medicine .
A small number of people being treated with antiepileptics such as phenytoin sodium have had thoughts of harming or killing themselves. If at any time you have these thoughts, immediately contact your doctor.
If you develop a rash or these skin symptoms, stop taking Phenytoin, seek urgent advice from a doctor and tell him that you are taking this medicine. Consult your doctor before discontinuing . If you suddenly stop taking this medicine you may have a seizure.
If you are taking phenytoin at the same time as you receive radiation therapy to your head and the dose of another medication called corticosteroids is reduced, you may more likely to develop a severe skin rash called erythema multiform or one that causes blistering called Stevens Johnson Syndrome or Toxic Epidermal Necrosis .
You should use Phenytoin with caution if you suffer from kidney or liver problems.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat.