SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Fosfomycin
Used For
Bacterial Infection
How it works
The bactericidal action of fosfomycin is due to its inactivation of the enzyme enolpyruvy transferase, thereby irreversibly blocking the condensation of uridine diphosphate N-acetylglucosamine with p-enolpyruvate, one of the first steps in bacterial cell wall synthesis. It also reduces adherence of bacteria to uroepithelial cells.
USAGE AND SAFETY
Dosage
Fosfomycin
Side Effects
Headache , rash , diarrhoea , nausea , vomiting , anorexia , pigastric discomfort , dizziness , fatigue , pruritis.
Drug Interactions
Antacids , metoclopramide & drugs altering GI motility.
Indication
It is indicated in : Urinary tract infections (+ catheter) caused by multiple resistant E. coli & Klebsiella organisms with proven resistance to all other antibiotics where no other appropriate agent is available.
When not to Use
Fosfomycin is contraindicated in patients with known hypersensitivity to the drug .
PRECAUTIONS
Precaution
Fosfomycin can lead to diarrhea during treatment. In case you have a severe or persistent diarrhea or if you notice that your stool contains blood or mucus, call your doctor immediately. Do not take any medicines which may stop or slow down bowel movement.
WARNINGS
Warning 1
Do not give this medicine to children and adolescents under 12 years of age because it has not been studied in this age group.
Warning 2
If you are pregnant or breast-feeding, or think you may be pregnant or are planning to have a baby, ask doctor for advice before taking this medicine.
Warning 3
Fosfomycin may cause dizziness and can therefore have minor influence on the ability to drive and use machines.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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