Ivirem Injection 100Mg

Name: Ivirem Injection 100Mg
Brand: NABIQASIM INDUSTRIES
Price: 5396

Brand : nabiqasim industries

Rs. 5,396.00

Rs. 5,680.00

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Ivirem Injection Specification

Requires Prescription (YES/NO)

Yes

Generics

Remdesivir

Used For

Viral Infection

How it works

Remdesivir is an adenosine nucleotide prodrug that distributes into cells where it is metabolized to form the pharmacologically active nucleoside triphosphate metabolite. Metabolism of remdesivir to remdesivir triphosphate has been demonstrated in multiple cell types. Remdesivir triphosphate acts as an analog of adenosine triphosphate (ATP) and competes with the natural ATP substrate for incorporation into nascent RNA chains by the SARS-CoV-2 RNA-dependent RNA polymerase, which results in delayed chain termination during replication of the viral RNA. Remdesivir triphosphate is a weak inhibitor of mammalian DNA and RNA polymerases with low potential for mitochondrial toxicity .

Ivirem Injection Usage And Safety

Dosage

Remdesivir

Side Effects

• Allergic reactions : Changes in your heart rate , rash , fever , nausea , shortness of breath, wheezing , sweating , swelling of the lips, face, or throat , shivering • Increase in liver enzymes : Increases in liver enzymes are common in people who have received Remdesivir and may be a sign of liver injury .

Drug Interactions

Ask your physician or pharmacist for any drug interaction.

Indication

It is used for the treatment of coronavirus disease 2019 (COVID-19) in adults and children 12 years of age and older and weighing at least 88 pounds (40 kg) who are: • Hospitalized, or • Not hospitalized and have mild-to-moderate COVID-19, and are at high risk for progression to severe COVID-19, including hospitalization or death.

When not to Use

Remdesivir is contraindicated in patients with known hypersensitivity to any ingredient of remdesivir.

Ivirem Injection Precautions

Precaution

Infusion-related reactions have been observed during, and/or been temporally associated with, administration of remdesivir. Signs and symptoms may include hypotension, nausea, vomiting, diaphoresis, and shivering. If signs and symptoms of a clinically significant infusion reaction occur, immediately discontinue administration of remdesivir and initiate appropriate treatment. The use of remdesivir is contraindicated in patients with known hypersensitivity to remdesivir.

Ivirem Injection Warnings

Warning 1

Remdesivir should not be initiated in patients with ALT = 5 times the upper limit of normal at baseline .

Warning 2

Remdesivir should be discontinued in patients who develop: ALT = 5 times the upper limit of normal during treatment with remdesivir. Remdesivir may be restarted when ALT is < 5 times the upper limit of normal. OR ALT elevation accompanied by signs or symptoms of liver inflammation or increasing conjugated bilirubin, alkaline phosphatase, or INR .

Warning 3

Remdesivir should be used during pregnancy only if the potential benefit justifies the potential risk for the mother and the fetus .

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