Kemocarb 150Mg Specification
Requires Prescription (YES/NO)
Yes
Generics
Carboplatin
Used For
Cancer
How it works
Carboplatin undergoes activation inside cells and forms reactive platinum complexes that cause the intra- and inter-strand cross-linkage of DNA molecules within the cell. This modifies the DNA structure and inhibits DNA synthesis. This may affect a cell in all the phases of its cycle .
Kemocarb 150Mg Usage And Safety
Dosage
Carboplatin
Side Effects
Bone marrow suppression , Nephrotoxicity , Nausea without vomiting , rash, urticaria, erythema, pruritus, and rarely bronchospasm and hypotension , Ototoxicity , Neurotoxicity , Hepatic , Pain and asthenia , cardiac failure, embolism, cerebrovascular accidents .
Drug Interactions
Aminoglycoside antibiotics
Indication
It is used to treat Advanced ovarian carcinoma of epithelial origin in : First line therapy second line therapy, after other treatments have failed ; Small cell carcinoma of the lung.
When not to Use
It should not be used in patients with severe pre-existing renal impairment. It should not be employed in severely myelosuppressed patients. It is also contraindicated in patients with a history of severe allergic reactions to carboplatin or other platinum containing compounds.
Kemocarb 150Mg Precautions
Precaution
Peripheral blood counts and renal function tests should be monitored closely. Blood counts at the beginning of the therapy and weekly to assess hematological nadir for subsequent dose adjustment are recommended. Neurological evaluations should also be performed on a regular basis.
Kemocarb 150Mg Warnings
Warning 1
It should only be administered under the supervision of a qualified physician who is experienced in the use of chemotherapeutic agents. Diagnostic and treatment facilities should be readily available for management of therapy and possible complications .
Warning 2
It can cause nausea and vomiting . Premedication with antiemetics has been reported to be useful in reducing the incidence and intensity of these effects.
Warning 3
In combination therapy with other myelosuppressive compounds must be planned very carefully with respect to dosages and timing in order to minimise additive effects. Supportive transfusional therapy may be required in patients who suffer severe myelosuppression.
Kemocarb 150Mg Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store in a refrigerator (2°C–8°C). Do not Freeze .
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