Ketasol Im/Iv Injection 100Mg 2Ml (1 Box = 5 Ampoules)

Name: Ketasol Im/Iv Injection 100Mg 2Ml (1 Box = 5 Ampoules)
Brand: INDUS PHARMA
Price: 2235.30

Brand : indus pharma

Rs. 2,235.30

Rs. 2,352.94

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Ketasol Im/Iv Specification

Requires Prescription (YES/NO)

Yes

Generics

Ketamine Hydrochloride

Used For

Anesthesia

How it works

Ketamine induces sedation, immobility, amnesia and marked analgesia. The anaesthetic state produced by ketamine has been termed “dissociative anaesthesia” in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectively depress the thalamoneocortical system before significantly obtunding the more ancient cerebral centres and pathways (reticular-activating and limbic systems). Numerous theories have been proposed to explain the effects of ketamine, including binding to N-methyl-D-aspartate (NMDA) receptors in the CNS, interactions with opiate receptors at central and spinal sites and interaction with norepinephrine, serotonin and muscarinic cholinergic receptors. The activity on NMDA receptors may be responsible for the analgesic as well as psychiatric (psychosis) effects of ketamine. Ketamine has sympathomimetic activity resulting in tachycardia, hypertension, increased myocardial and cerebral oxygen consumption, increased cerebral blood flow and increased intracranial and intraocular pressure. Ketamine is also a potent bronchodilator. Clinical effects observed following ketamine administration include increased blood pressure, increased muscle tone (may resemble catatonia), opening of eyes (usually accompanied by nystagmus) and increased myocardial oxygen consumption.

Ketasol Im/Iv Usage And Safety

Dosage

Ketamine Hydrochloride

Side Effects

• Hallucinations (which may include flashbacks or floating sensation), vivid dreams, nightmares, feeling ill at ease, confused, anxious and irrational behaviour. • Unusual eye movements, increased muscle tone and muscle twitches (which may resemble ‘fits’ or convulsions) , • Double vision. • Increased blood pressure and increased pulse rate • Breathing more quickly. • Nausea, vomiting. • Skin inflammation/rash.

Drug Interactions

Barbiturates or narcotics (morphine-like drugs ) , atracurium and tubocurarine , halogenated anaesthetics , phenothiazines , sedating antihistamines , anxiolytics, sedatives and hypnotics , ‘Z-drugs’ (e.g.zolpidem , barbiturates (e.g. phenobarbital) , thyroid hormones (medicines like thyroxine), Diazepam , sympathomimetics (for example adrenaline or noradrenaline) or vasopressin , ergometrine , theophylline oraminophylline

Indication

It is used to put you to sleep during an operation. Ketamine may be used in both routine and emergency surgery.

When not to Use

Do not use Ketamine: • If you are allergic to ketamine hydrochloride or any of the other ingredients of this medicine . • If you are suffering from any condition in which an increase in blood pressure may be harmful to you or have suffered in the past from a medical condition which may have been caused/made worse by an increase in blood pressure. • If you have been pregnant and during your pregnancy you have suffered from a condition called eclampsia or pre-eclampsia which causes an increase in your blood pressure.

Ketasol Im/Iv Precautions

Precaution

To be used only in hospitals by or under the supervision of experienced medically qualified anaesthetists except under emergency conditions.

Ketasol Im/Iv Warnings

Warning 1

Respiratory depression may occur with overdosage of Ketamine, in which case supportive ventilation should be employed. Mechanical support of respiration is preferred to the administration of analeptics.

Warning 2

The intravenous dose should be administered over a period of 60 seconds. More rapid administration may result in transient respiratory depression or apnoea and enhanced pressor response.

Warning 3

Because pharyngeal and laryngeal reflexes usually remain active, mechanical stimulation of the pharynx should be avoided unless muscle relaxants, with proper attention to respiration, are used.

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