Ketoalfa Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Alpha Keto Analogue
Used For
Kidney Disease
How it works
Following absorption, the keto- and hydroxy-analogues are transaminated to the corresponding essential amino acids by taking nitrogen from non-essential amino acids, thereby decreasing the formation of urea by re-using the amino group. Hence, the accumulation of uraemic toxins is reduced. Keto and hydroxy acids do not induce hyperfiltration of the residual nephrons. Ketoacid containing supplements exert a positive effect on renal hyperphosphataemia and secondary hyperparathyroidism. Moreover, renal osteodystrophy may be improved. The use in combination with a very low protein diet allows to reduce nitrogen intake while preventing the deleterious consequences of inadequate dietary protein intake and malnutrition.
Ketoalfa Tablets Usage And Safety
Dosage
Alpha Keto Analogue
Side Effects
Hypercalcaemia .
Drug Interactions
Tetracyclines, quinolines such as ciprofloxacin and norfloxacin as well as drugs containing iron, fluoride or estramustine , aluminium hydroxide .
Indication
Prevention and treatment of damages due to faulty or deficient protein metabolism in chronic kidney disease in connection with a limited dietary protein intake of 40 g/day or less (adult). Usually this applies to patients whose glomerular filtration rate (GFR) is less than 25 mL/min.
When not to Use
Hypersensitivity to the active substances or to any of the excipients ; Hypercalcaemia ; Disturbed amino acid metabolism.
Ketoalfa Tablets Precautions
Precaution
The serum calcium level should be monitored regularly. Ensure sufficient calorie intake .
Ketoalfa Tablets Warnings
Warning 1
No experience has been gained so far with the administration in paediatric patients.
Warning 2
In the presence of hereditary phenylketonuria, attention should be given to the fact that contains phenylalanine. Monitoring of the serum phosphate levels is needed in case of concomitant administration of aluminium hydroxide .
Warning 3
It has no influence on the ability to drive and use machines.
Ketoalfa Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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