Myrin-P Forte Tablets 80S (Pack Size 10 X 8S)
Brand : wyeth pharma
How it works
The mechanism of action of ethambutol is not fully known. It diffuses into mycobacteria and appears to suppress multiplication by interfering with RNA synthesis. It is effective only against mycobacteria that are actively dividing.Rifampicin inhibits bacterial RNA synthesis by bonding strongly to the beta subunit of DNA-dependent RNA polymerase, preventing the attachment of the enzyme to DNA and thus blocking initiation of RNA transcription.Isoniazid is a bactericidal antitubercular agent which is active against actively dividing mycobacteria and its mode of action may relate to inhibition of mycolic acid synthesis and the disruption of the cell wall in susceptible organisms.The mechanism of action of pyrazinamide is unknown. Pyrazinamide may be bacteriostatic or bactericidal depending on its concentration and the susceptibility of the organism.
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