Oculerg Eye Specification
Requires Prescription (YES/NO)
Yes
Generics
Antazoline HCl , Tetrahydrozoline HCl
Used For
Eye Infection
How it works
Antazoline is an anti-histamine of the ethylenediamine class, which are selective H1-antagonists. When used systemically, this group of anti- histamines can cause moderate sedation (despite having weak CNS effects), gastric disturbances, and skin sensitisation. Antazoline competitively blocks H1 receptors. Effects mediated by H1 receptors include the contraction of smooth muscle and the dilatation and increased permeability of the capillaries. Tetryzoline is a sympathomimetic with alpha adrenergic activity. Its vasoconstrictive effect reduces redness and oedema in allergic conjunctivitis. Antihistamines, which act by blocking the H1 histamine receptor, are highly effective in providing relief of itching but are not very active in relieving the associated redness. The use of products combining an anti-histamine and vasoconstrictor is well established in the symptomatic relief of allergic eye disease.
Oculerg Eye Usage And Safety
Dosage
Antazoline HCl , Tetrahydrozoline HCl
Side Effects
Patients may experience any of the adverse effects noted for each of the individual active substances. The most common adverse effect is burning/stinging upon instillation, which is mild and transient in nature
Drug Interactions
Sympathomimetic agents may cause a hypertensive crisis if used during treatment with MAOIs. Concomitant use with MAOIs is therefore contraindicated . Sedating anti-histamines can enhance the sedating effects of CNS depressants including alcohol, hypnotics, opioid analgesics, anxiolytic sedatives and anti-psychotics. They also have an additive anti-muscarinic action with other antimuscarinic drugs, such as atropine and some antidepressants (both tricyclics and MAOIs). As systemic absorption of antazoline is possible, caution should be exercised when using Spersallerg concomitantly with these medicinal products.
Indication
Temporary relief of the signs and symptoms of allergic conjunctivitis including conjunctival hyperaemia, chemosis and itching in adults and children above 2 years of age.
When not to Use
?Known hypersensitivity to antazoline and / or tetryzoline or to any of the excipients.?Concomitant use with Monoamine Oxidase Inhibitors (MAOI) .
Oculerg Eye Precautions
Precaution
If the patient wears contact lenses, these should be removed before instillation and not reinserted for at least 15 minutes. Furthermore, antazoline in multidose containers contains the preservative benzalkonium chloride, which may cause eye irritation and is known to discolour soft contact lenses.
Oculerg Eye Warnings
Warning 1
It is not suitable for patients suffering from dry eyes without first seeking medical advice. Patients experiencing symptoms of dry eyes should discontinue the use of this product and seek the advice of their medical practitioner. Eye infections may be masked by the use of this medicine.
Warning 2
Care should be taken in patients at risk of or with angle closure glaucoma, unless iridectomy (or iridotomy) has been performed. Patients should be informed that overuse of vasoconstrictors may produce rebound hyperaemia.
Warning 3
Sympathomimetic drugs should be used with caution in patients with diabetes, hypertension, hyperthyroidism and elevated thyroid hormone concentrations, arrhythmias or tachycardia and phaeochromocytomas.
Oculerg Eye Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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