Prelox Tablets 100Mg

Brand : bosch pharmaceuticals

Rs. 361.00

Rs. 380.00

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SPECIFICATION

Requires Prescription (YES/NO)

Yes

Generics

Cefpodoxime

Used For

Bacterial Infection

How it works

Cefpodoxime is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Cefpodoxime has activity in the presence of some beta-lactamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria.

USAGE AND SAFETY

Dosage

Cefpodoxime

Side Effects

Cardiovascular - congestive heart failure, migraine, palpitations, vasodilation, hematoma, hypertension, hypotension.Digestive - vomiting, dyspepsia, dry mouth, flatulence, decreased appetite, constipation, oral moniliasis, anorexia, eructation, gastritis, mouth ulcers, gastrointestinal disorders, rectal disorders, tongue disorders, tooth disorders, increased thirst, oral lesions, tenesmus, dry throat, toothache.Hemic and Lymphatic - anemia Metabolic and Nutritional - dehydration, gout, peripheral edema, weight increase.Musculo-skeletal - myalgia.Nervous - dizziness, insomnia, somnolence, anxiety, shakiness, nervousness, cerebral infarction, change in dreams, impaired concentration, confusion, nightmares, paresthesia, vertigo.Respiratory - asthma, cough, epistaxis, rhinitis, wheezing, bronchitis, dyspnea, pleural effusion, pneumonia, sinusitis.Skin - urticaria, rash, pruritus non-application site, diaphoresis, maculopapular rash, fungal dermatitis, desquamation, dry skin non-application site, hair loss, vesiculobullous rash, sunburn. Urogenital - hematuria, urinary tract infections, metrorrhagia, dysuria, urinary frequency, nocturia, penile infection, proteinuria, vaginal pain.

Drug Interactions

Antacids (sodium bicarbonate and aluminum hydroxide) or H2 blockers , Oral anti-cholinergics (e.g., propantheline) , Probenecid , Nephrotoxic drugs.

Indication

Cefpodoxime is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below : Acute otitis media caused by Streptococcus pneumoniae , Pharyngitis and/or tonsillitis caused by Streptococcus pyogenes , Community-acquired pneumonia caused by S. pneumoniae or H. Influenzae (including beta-lactamase-producing strains) , Acute bacterial exacerbation of chronic bronchitis caused by S. pneumoniae, H. influenzae (non-beta-lactamase-producing strains only), or M. catarrhalis. Data are insufficient at this time to establish efficacy in patients with acute bacterial exacerbations of chronic bronchitis caused by beta-lactamase-producing strains of H. influenzae. Acute, uncomplicated urethral and cervical gonorrhea caused by Neisseria gonorrhoeae (including penicillinase-producing strains).

When not to Use

Cefpodoxime is contraindicated in patients with a known allergy to cefpodoxime or to the cephalosporin group of antibiotics.

PRECAUTIONS

Precaution

In patients with transient or persistent reduction in urinary output due to renal insufficiency, the total daily dose of cefpodoxime proxetil should be reduced because high and prolonged serum antibiotic concentrations can occur in such individuals following usual doses. Cefpodoxime, like other cephalosporins, should be administered with caution to patients receiving concurrent treatment with potent diuretics.

WARNINGS

Warning 1

Careful medical history is necessary since C. difficile-associated disease (CDAD) has been reported to occur over two months after the administration of antibacterial agents.

Warning 2

It should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold).

Warning 3

Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.