Provate-G Cream 15G

How it works

Topical corticosteroids act as anti-inflammatory agents via multiple mechanisms to inhibit late phase allergic reactions including decreasing the density of mast cells, decreasing chemotaxis and activation of eosinophils, decreasing cytokine production by lymphocytes, monocytes, mast cells and eosinophils, and inhibiting the metabolism of arachidonic acid. Gentamicin is bactericidal and is a broad spectrum antibiotic (except against streptococci and anaerobic bacteria). Its mechanism of action involves inhibition of bacterial protein synthesis by binding to 30S ribosomes.

Description

PROVATE-G CREAM 15 GM

Generics

Betamethasone Dipropionate , Gentamicin

used for

Topical Antibacterial

Requires Prescription (YES/NO)

Yes

Indication

It is used in localised, small-area skin conditions, when: • These require treatment with a potent glucocorticoid and • An additional infection (superinfection) with bacteria is present at the same time • These bacteria can be effectively treated with the active substance gentamicin.

Side Effects

Skin and subcutaneous tissue disorders : Burning, pruritus (itching), skin irritation, dry skin, folliculitis (inflammation of the hair follicles), hypertrichosis (increased hair growth), steroid acne (acne-like rash), changes in skin pigmentation, skin rosacea-like (perioral) dermatitis (inflammation around the mouth), allergic contact dermatitis , maceration of the skin (swelling of the skin), skin atrophy (thinning of the skin), striae (stretch marks) and miliaria (blistering), erythema, hypersensitivity, skin discoloration. Musculoskeletal, connective tissue and bone disorders : Delayed length growth in children. Vascular disorders : Intracranial hypertension in children (bulging fontanelles, headache, swelling of the optic nerve). Metabolism and nutrition disorders: Decreased weight gain in children. Eye disorders : Blurred vision.

When not to Use

Do not use - If you are allergic to betamethasone or gentamicin, to other medicines from the group of glucocorticoids or aminoglycoside antibiotics or to any of the other ingredients of the medicine .- For viral infections, including vaccination reactions and chickenpox,- For tuberculosis or syphilis involving the skin,- For viral infections of the skin (e.g. herpes simplex, shingles),- Skin rash around the mouth

Dosage

Adults & Children : Apply three or four times daily. OR As directed by your physician.

Storage yes or /no

Store this medicine at room temperature, away from direct light and heat.

Precautions

Do not use this medicine in the ear canal, eyes or on mucous membranes. In case of accidental contact with eyes, rinse with plenty of water and consult an ophthalmologist if necessary .

Warning 1

Do not use with air tight occlusive dressings (e.g. under bandages , nappies).

Warning 2

The effect of glucocorticoids in the body when applied to the skin generally increases with their strength (potency), duration of use, the extent of treated body surface areas and when used in skin folds.

Warning 3

Due to possible absorption of the active substances into the body, long-term treatment and/or use over large skin areas should be avoided. Ask your doctor if you are not sure whether you have a widespread skin condition.

Pregnancy category

Always consult your physician before using any medicine.

Drug Interactions

Amphotericin B , heparin , sulfadiazine , beta-lactam antibiotics (e.g. cephalosporins).

Brand : saffron pharmaceutical comp

Per pc

Rs. 104.66

Rs. 110.17

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