INDICATIONS : Osteo-arthritis especially of the large joints, arthritis of the knee and hipjoint, osteo-arthritis of the vertebrae. MODE OF ACTION OF MAIN INGREDIENTS: The ingredients contained in this preparation influence the metabolism of cartilage in particular. Long term medication is necessary before definite improvement sets in. This is best explained by the fact osteo-arthritis is a gradual degenerative process. Acidum sulfuricum: Arthralgia in different joints. Markedly influences the metabolism of cartilage. Argentum: Arthralgia associated with degeneration of joints. Arnica: Painful joints. Bryonia: Swollen, stiff joints, worse on movement. Causticum Hahnemanni: Joint deformity associated with paralytic weakness and stiffness. Ledum: Rheumatic joint pain, cramping pain in hip area. DOSAGE : To begin with give 10-15 drops in some water 4-6 times daily . After 2-3 weeks treatment the dosage may be reduced to 2-3 times daily .