
Requip 1Mg Tablets 21S (Pack Size 3 X 7S)
Brand : glaxo smith kline pakistan
Per Strip
Rs. 262.22
Rs. 276.00
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How it works
Ropinirole is a non-ergoline dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. Ropinirole has moderate in vitro affinity for opioid receptors. Ropinirole and its metabolites have negligible in vitro affinity for dopamine D1, 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, alpha1-, alpha2-, and beta-adrenoreceptors.
Description
REQUIP TAB 1 MG 21'S
Generics
Ropinirole
used for
Anti-Parkinson
Requires Prescription (YES/NO)
Yes
Indication
It helps to reduce the symptoms of Parkinson’s disease.
Side Effects
Very common side effects: may affect more than 1 in 10 people • fainting • feeling drowsy • feeling sick(nausea).Common side effects: may affect up to 1 in 10 people • hallucinations (sensing things that are not real) • being sick (vomiting) • feeling dizzy (a spinning sensation) • heartburn • stomach pain • swelling of the legs, feet or hands.Uncommon side effects: may affect up to 1 in 100 people • feeling dizzy or faint, especially when you stand up suddenly (this is caused by a drop in blood pressure) • feeling very sleepy during the day (extreme somnolence) • falling asleep very suddenly without feeling sleepy first (sudden sleep onset episodes) • mental problems such as delirium (severe confusion), delusions (unreasonable ideas) or paranoia(unreasonable suspicions).
When not to Use
Do not take Ropinirole: • if you are allergic to ropinirole or any of the other ingredients of this medicine .• If you have serious kidney disease• If you have liver disease
Dosage
Parkinson's : Adults : The usual starting dose is 0.25 mg of ropinirole three times each day for the first week. Then your doctor will increase your dose each week, for the next three weeks. After that, your doctor will gradually increase the dose until you are taking the dose that is best for you. The usual is 1 mg to 3 mg three times each day (making a total daily dose of 3 mg to 9 mg). If your Parkinson’s disease symptoms have not improved enough, your doctor may decide to gradually increase your dose some more. Some people take up to 8mg of Ropinirole three times a day (24 mg daily altogether). Children : Not recommended. Always consult with your doctor or pharmacist for dose adjustments.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Precautions
It may potentiate the dopaminergic side effects of L-dopa and may cause and/or exacerbate preexisting dyskinesia in patients treated with L-dopa for Parkinson's disease. Decreasing the dose of L-dopa may ameliorate this side effect.
Warning 1
Tell your doctor if you or your family/carer notices that you are developing urges or cravings to behave in ways that are unusual for you and you cannot resist the impulse, drive or temptation to carry out certain activities that could harm yourself or others. These are called impulse control disorders and can include behaviours such as addictive gambling, excessive eating or spending, an abnormally high sex drive or an increase in sexual thoughts or feelings. Your doctor may need to adjust or stop your dose.
Warning 2
Do not give Ropinirole children. Ropinirole not normally prescribed for people under 18.
Warning 3
Tell your doctor if you experience symptoms such as depression, apathy, anxiety, lack of energy, sweating or pain after stopping or reducing your Requip treatment. If the problems persist more than a few weeks, your doctor may need to adjust your dose.
Pregnancy category
Always consult your physician before using any medicine.
Drug Interactions
• Anti-depressant fluvoxamine , • HRT (hormone replacement therapy) • the antibiotics ciprofloxacin or enoxacin • medication for other mental health problems, for example sulpiride • metoclopramide, which is used to treat nausea andheartburn • cimetidine, used in the treatment of stomach ulcers • any other medicine for Parkinson’s disease.
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