Ronim Iv Injection 500Mg (1 Box = 1 Injection)

Name: Ronim Iv Injection 500Mg (1 Box = 1 Injection)
Brand: GENIX PHARMA PRIVATE LIMITED
Price: 2061.86

Brand : genix pharma private limited

Rs. 2,061.86

Rs. 2,170.38

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Ronim Iv Specification

Requires Prescription (YES/NO)

Yes

Generics

Doripenem

Used For

Bacterial Infection

How it works

Doripenem belongs to the carbapenem class of antimicrobials. Doripenem exerts its bactericidal activity by inhibiting bacterial cell wall biosynthesis. Doripenem inactivates multiple essential penicillin-binding proteins (PBPs) resulting in inhibition of cell wall synthesis with subsequent cell death. In E. coli and P. aeruginosa, doripenem binds to PBP 2, which is involved in the maintenance of cell shape, as well as to PBPs 3 and 4.

Ronim Iv Usage And Safety

Dosage

Doripenem

Side Effects

Gastrointestinal disorders : Diarrhea , Nausea , Vomiting ; Investigations : Hepatic enzyme increased , Gamma-glutamyltransferase increased ; Nervous system disorders : Headache , Vascular disorders , Phlebitis ; Skin and subcutaneous tissue disorders : Rash

Drug Interactions

Probenecid , Valproic Acid .

Indication

It is indicated for the treatment of the following infections in adults : • Nosocomial pneumonia (including ventilator–associated pneumonia) • Complicated intra-abdominal infections • Complicated urinary tract infections .

When not to Use

It is contraindicated in patients with known serious hypersensitivity to doripenem or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams.

Ronim Iv Precautions

Precaution

Administration of doripenem, like other antibiotics, has been associated with emergence and selection of strains with reduced susceptibility. Patients should be carefully monitored during therapy. If superinfection occurs, appropriate measures should be taken. Prolonged use of Doripenem should be avoided.

Ronim Iv Warnings

Warning 1

Serious and occasionally fatal hypersensitivity (anaphylactic) and serious skin reactions have been reported in patients receiving beta-lactam antibiotics. These reactions are more likely to occur in individuals with a history of sensitivity to multiple allergens. Before therapy with Doripenem is instituted, careful inquiry should be made to determine whether the patient has had a previous hypersensitivity reaction to other carbapenems, cephalosporins, penicillins or other allergens. If this product is to be given to a penicillin- or other beta-lactam-allergic patient, caution should be exercised because cross-hyperreactivity among beta-lactam antibiotics has been clearly documented .

Warning 2

Seizures have infrequently been reported during treatment with other carbapenems .

Warning 3

Pseudomembranous colitis due to Clostridium difficile has been reported with Doripenem as with nearly all anti-bacterial agents and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhoea during or subsequent to the administration of Doripenem .

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