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    Dvago

    Thiolax 4Mg Capsules 20S (Pack Size 2 X 10S)

    Rs. 295.00

    Rs. 310.50

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    SPECIFICATION

    Requires Prescription (YES/NO)

    Yes

    Generics

    Thiocolchicoside

    Used For

    Muscle Spasms

    How it works

    Thiocolchicoside has a selective and potent af?nity for g-aminobutyric acid A (GABA-A) receptors and acts on muscular contractures by activating the GABA inhibitory pathways thereby behaving as a potent muscle relaxant .

    USAGE AND SAFETY

    Dosage

    Thiocolchicoside

    Side Effects

    Generally the drugs is well-tolerated. In rare cases diarrhea, gastric pain and heartburn may occur. In very rare cases, drowsiness may also occur infrequent cases of skin rash or erythema have been reported.

    Drug Interactions

    Taking Thiocolchicoside with other drugs which acting muscle relaxants on the musculoskeletal system are not recommended because they may enhance the effect of another .

    Indication

    As an adjuvant treatment in painful spasm associated with degenerative vertebral disorders and vertebral static problem, torticollis, dorsal pain, low back pain, traumatological and neurological disorders.

    When not to Use

    Hypersensitivity to thiocolchicoside or one of its excipients; pregnancy and lactation; in women of child bearing potential not using effective contraceptive.

    PRECAUTIONS

    Precaution

    If diarrhea appears after oral administration the dosage should be reduced.

    WARNINGS

    Warning 1

    In preclinical studies, one of thiocolchicoside metabolites induced aneuploidy at concentrations close to human exposure observed at doses 8 mg twice daily. Aneuploidy is reported as a risk factor for teratogenicity, embryofoetotoxicity/spontaneous abortion, cancer, and impaired male fertility. As a precautionary measure, use of the product at doses exceeding the recommended dose or long term use should be avoided.

    Warning 2

    Postmarketing cases of cytolytic and cholestatic hepatitis have been reported. Severe cases in patients concomitantly taking NSAIDs or paracetamol. Patients should be advised to stop treatment and report any sign of liver toxicity.

    Warning 3

    Thiocolchicoside may precipitate seizures, especially in patients with epilepsy or those at risk for seizures. Patients should be carefully informed about the potential risk of a possible pregnancy and about effective contraceptive measures to be followed.

    ADDITIONAL INFORMATION

    Pregnancy category

    Always consult your physician before using any medicine.

    Storage (YES/NO)

    Store this medicine at room temperature, away from direct light and heat.

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