Vancomycin 500Mg/Vial Injection 10Ml
Brand : abbot laboratories (pak) ltd
How it works
The bactericidal action of Vancomycin results primarily from inhibition of cell-wall biosynthesis. In addition, Vancomycin alters bacterial-cell membrane permeability and RNA synthesis. There is no cross-resistance between Vancomycin and other antibiotics.
VANCOMYCIN INJ 500 MG 1 VIAL
Requires Prescription (YES/NO)
Serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci, pencillin-alergic patients. For infections caused by vancomycin susceptible organisms for initial therapy, when methicillin resistant staphylococci are suspected. In the treatment of staphylococcal endocarditis, infections due to staphylococci, including septicemia, bone infections, lower respiratory tract infections, and skin & skin structure infections.
Infusion related events , nephrotoxicity , ototoxicity , neutropenia , nausea , chills , fever , rashes , eosinophillia , phlebitis , decreased BP , dyspnoea , stridor , pruritis , mucosal inflammation , severe pain at inj site.
When not to Use
Vancomycin HCI is contraindicated in patients with known hypersensitivity to this antibiotic.
Adults: The usually daily intravenous dose is 2 g divided either as 500 mg every 6 hours or 1 g every 12 hours . Each dose should be administered over a period of atleast 60 minutes. Other patient factors such as age or obesity,may call for modification of the usual daily dose. Children: The total daily intravenous dosage of Vancomycin Hydrochloride calculated on the basis of 40 mg/kg of body weight, can be divided and incorporated into the Child's 24hours fluid required.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
In order to minimise the risk of nephrotoxicity when treating patients with underlying renal dysfunction or patients receiving concomitant therapy with an aminoglycoside. Serial monitoring or renal function should be performed and particular care should be taken in following appropriate dosing schedules.
Rapid bolus administration (e.g. Over several minutes) may be associated with exaggerated hypotension and rarelycardiac a rest.
Vancomycin HCI should be administered in a diluted solution over a period of not less than 60 minutes to avoid rapid-infusion-related reactions. Stopping the infusion usually results in prompt cessation of there reactions.
Ototoxicity has occurred in patients receiving Vancomycin HCI. It may be transient or permanent. It has been reported mostly in patients who have given excessive doses. who have an underfying hearing loss, or who are receiving concomitant therapy with another ototoxic agent,such as an aminoglycoside .
Always consult your physician before using any medicine.
Neurotoxic , ototoxic or nephrotoxic drugs , anesthetics , PPIs , antimotility agents.
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