Cyclomide Iv Injection 1G (1 Box = 1 Injection)

Name: Cyclomide Iv Injection 1G (1 Box = 1 Injection)
Brand: PHARMADIC
Price: 496.85

Brand : pharmadic

Rs. 496.85

Rs. 523.00

|

QUICK DELIVERY

Cyclomide Iv Specification

Requires Prescription (YES/NO)

Yes

Generics

Cyclophosphamide

Used For

Cancer

How it works

Cyclophosphamide has been demonstrated to have a cytostatic effect in many tumour types. Cyclophosphamide engages probably to the S-or G2-phase of the cell cycle . It remains to be shown whether the cytostatic effect is entirely dependent on the alkylation of DNA or other mechanisms such as inhibition of chromatin transformation processes or inhibition of DNA polymerases play a role. The metabolite acrolein has no antineoplastic activity, but is responsible for the adverse urotoxic effect.

Cyclomide Iv Usage And Safety

Dosage

Cyclophosphamide

Side Effects

• Decrease in the activity of your bone marrow (myelosuppression). This can cause a decrease in the number of white cells (which fight infection) in your blood (Leucopenia, Neutropenia); • Hair loss (alopecia); • Pain and difficultly passing urine (cystitis); • Blood in the urine (haematuria); • Fever

Drug Interactions

• Allopurinol • Azathioprine • Busulfan • Chloral hydrate • Cimetidine • Disulfiram • Glyceraldehyde • Protease inhibitors • Rifampicin , carbamazepine, phenobarbital, phenytoin • Etanercept • Metronidazole •Tamoxifen • Bupropion • Coumarins such as warfarin • Cyclosporine • succinylcholine • digoxin .

Indication

Cyclophosphamide is used alone or together with other anti-cancer medicines or radiotherapy for different types of cancer .

When not to Use

You will not be given Cyclophosphamide if: • You have ever had an allergic reaction to cyclophosphamide. An allergic reaction can include shortness of breath, wheezing, rash, itching or swelling of the face and lips. • Your bone marrow is not working properly (especially if you have previously had chemotherapy or radiotherapy). You will have blood tests to check how well your bone marrow is working. • You have a urinary tract infection, which can be recognised as pain when passing urine (cystitis).

Cyclomide Iv Precautions

Precaution

Infections occurring during treatment with cyclophosphamide, including neutropenic fever, must be treated appropriately. Antimicrobial prophylaxis may be indicated in certain cases of neutropenia (at the discretion of the managing physician). In case of neutropenic fever, antibiotics and/or antimycotics must be given. Cyclophosphamide must be administered with the necessary caution (or not at all) in patients with severe functional impairment of bone marrow and patients with severe immunosuppression.

Cyclomide Iv Warnings

Warning 1

Anaphylactic reactions including those with fatal outcomes have been reported in association with cyclophosphamide. Possible cross-sensitivity with other alkylating agents has been reported.

Warning 2

Cyclophosphamide treatment may not be indicated, or should be interrupted, or the dose reduced, in patients who have or who develop a serious infection.

Warning 3

Severe myelosuppression must be expected particularly in patients pre-treated with and/or receiving concomitant chemotherapy and/or radiation therapy.

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