Amkay 100Mg/2Ml I.V/I.M Injection 5X2mlampoule
Brand : bosch pharmaceuticals
Per Box
Rs. 375.35
Rs. 395.10
How it works
The primary mechanism of action of amikacin is the same as that for all aminoglycosides. It binds to bacterial 30S ribosomal subunits and interferes with mRNA binding and tRNA acceptor sites, interfering with bacterial growth.
Description
AMKAY 100MG INJ 5'S
Generics
Amikacin
used for
Bacterial Infection
Requires Prescription (YES/NO)
Yes
Indication
It is used in the treatment of serious infections caused by bacteria sensitive to amikacin.
Side Effects
• Ringing in your ears or loss of hearing • decrease in the amount of urine you produce • severe allergic reaction - you may experience a sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), and you may feel you are going to faint • skin rash • nausea and vomiting • an excessive build up of bacteria or yeast which are resistant to amikacin re side-effects may affect up to 1 in 1,000 people are listed below: • dizziness or vertigo (spinning sensation) • headache • fever • unusually low amount of red blood cells in the blood (anaemia) or excessiveamounts of the white blood cells known as eosinophils in the blood (eosinophilia) • low levels of magnesium in the blood .
When not to Use
Do not use Amikacin • If you have shown signs of hypersensitivity (severe allergy) to amikacin, or any of the other ingredients • If you suffer from a disorder called myasthenia gravis (severe weakness of certain muscles of the body) .
Dosage
Adults : 15mg/kg IM or IV daily in two divided doses for upto 10 days; total max 15gm. Children : Neonates, initially 10mg/kg then 15mg/kg daily intwo divided doses; others same as adult. Lower respiratory Infections : IV : Adults , Children & Other infants : 7.5mg/kg every 12hr or 5mg/kg IM/IV every 8hr. Max : 1.5gm/day. Neonates : Loading dose : 10mg/kg. Maintenance : 7.5mg/kg every 12hr. Always ask your doctor or pharmacist for dose adjustments.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Precautions
Amikacin should be used with caution in patients with history of kidney diseases, vertigo, hearing loss, mysthenia gravis, parkinsonisms.
Warning 1
Use with caution in patients who are sensitive to aminoglycosides.
Warning 2
Keep patients well hydrated to prevent chemical irritation or nephrotoxic reactions. Take appropriate measures in case of secondary infections .
Warning 3
Elderly patients may have reduced renal function which may not be evident in routine screening tests such as BUN or serum creatinine. A creatinine clearance determination may be more useful. Monitoring of renal function in elderly patients during treatment with aminoglycosides is particularly important.
Pregnancy category
Always consult your physician before using any medicine.
Drug Interactions
• Diuretics (water tablets) such as furosemide and ethacrynic acid • Other antibiotics that can affect your kidneys, hearing or balance • Anaesthetics or muscle-relaxing drugs • Indomethacin (an anti-inflammatory medicine) • Other antibiotics called beta-lactamases such as penicillin’s or cephalosporins • Bisphosphonates; drugs used to treat loss of bone mass • vitamin B1 (thiamine) • Platinum compounds used in chemotherapy such as cisplatin.
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