
Avsar Plus 320/10/25Mg Tablets 28S (Pack Size 4 X 7S)
Brand : pharmevo (private) limited.
Rs. 114.03
Rs. 120.00
|
QUICK DELIVERY
SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Valsartan, Amlodipine and Hydrochlorothiazide
Used For
Hypertension
How it works
Valsartan : Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II). Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Amlodipine is a dihydropyridine calcium channel blocker Amlodipine binds to both dihydropyridine and non-dihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Hydrochlorothiazide : The mode of action of thiazides is through inhibition of the Na+Cl- symporter perhaps by competing for the Cl- site, thereby affecting the renal tubular mechanisms of electrolyte reabsorption, directly increasing excretion of sodium and chloride in approximately equivalent amounts and indirectly, reducing plasma volume, with consequent increases in plasma renin activity, increases in aldosterone secretion, increases in urinary potassium loss, and decreases in serum potassium.
USAGE AND SAFETY
Dosage
Valsartan, Amlodipine and Hydrochlorothiazide
Side Effects
Agranulocytosis, bone marrow failure , Hemoglobin and Hematocrit decreased , Hemolytic anemia , Leukopenia, Neutropenia , Thrombocytopenia sometimes with purpura , Aplastic anemia , Anorexia , Hypercalcaemia , Hyperglycemia , Hyperlipidemia , Hyperuricaemia , Hypochloraemic alkalosis , Hypokalemia , Hypomagnesaemia , Headache , Hypertonia , Visual disturbance , Arrhythmias (including bradycardia, ventricular tachycardia, and atrial fibrillation).
Drug Interactions
Amlodipine : CYP3A4 inhibitors (protease inhibitors: ritonavir, azole antifungals: ketoconazole or itraconazole, macrolides: erythromycin or clarithromycin, verapamil or diltiazem) , CYP3A4 inducers (e.g. anticonvulsants: carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone; rifampicin and Hypericum perforatum ) , Sildenafil , Simvastatin , Immunosuppressants , Dantrolene infusion , Grape fruit. Valsartan : Potassium-sparing diuretics (e.g., spironolactone, triamterene, amiloride) , heparin , NSAIDs, including selective COX-2 inhibitors , rifampicin, ciclosporin , ritonavir , Lithium . Hydrochlorothiazide Metformin , antidepressants, antipsychotics, antiepileptics such as carbamazepine , cholestyramine or colestipol , Cyclosporine , Lithium , Alcohol, barbiturates or narcotics , Amantadine , Beta blockers and diazoxide , Cytotoxic agents , Digitalis glycosides , Iodine contrasting agents , Methyldopa , tubocurarine.
Indication
It (Valsartan, Amlodipine and Hydrochlorothiazide) is indicated for the treatment of essential hypertension in adults.
When not to Use
• Hypersensitivity condition to valsartan, amlodipine, hydrochlorothiazide or other sulphonamide or dihydropyridine derivatives.• Second and third trimesters of pregnancy• Severe hepatic impairment, biliary cirrhosis or cholestasis.
PRECAUTIONS
Precaution
It should be used with caution in patients with unilateral or bilateral renal artery stenosis or stenosis to a solitary kidney since blood urea and serum creatinine may increase in such patients.
WARNINGS
Warning 1
Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations.
Warning 2
In patients with an activated renin-angiotensin system, such as volume and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. This condition should be corrected prior to administration of Valsartan/amlodipine/HCT, or the treatment should start under close medical supervision.
Warning 3
Changes in renal function including acute renal failure can be caused by drugs that inhibit the renin-angiotensin system and by diuretics.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Related Products
Rs. 385.77
Rs. 406.07
masdipine sr 30mg tablets 20s (pack size 2x10s)
Rs. 228.00
Rs. 240.00
Rs. 279.30
Rs. 294.00
Rs. 345.80
Rs. 364.00
amstan 5/160mg tablets 14s (pack size 1x14s)
Rs. 891.94
Rs. 938.84
Rs. 211.80
Rs. 223.00
Rs. 389.20
Rs. 409.64
Rs. 399.00
Rs. 420.00
Rs. 532.00
Rs. 560.00
Rs. 532.00
Rs. 560.00
Rs. 295.40
Rs. 311.00
Rs. 385.70
Rs. 406.00
labetalol 100mg tablets 20s (pack size 2 x 10s)
Rs. 101.10
Rs. 106.45
cardace 5mg tablets 20s (pack size 2 x 10s)
Rs. 29.10
Rs. 30.62
cardace 10mg tablets 20s (pack size 2 x 10s)
Rs. 115.40
Rs. 121.54
atenolol 100mg tablets 20s (pack size 2 x 10s)
Rs. 125.60
Rs. 132.20
eziday 100mg tablets 10s (pack size 1 x 10s)
Rs. 302.90
Rs. 318.89
eziday 50mg tablets 20s (pack size 1 x 20s)
Rs. 454.20
Rs. 478.00
zodip 5mg tablets 20s (pack size 2 x 10s)
Rs. 36.10
Rs. 38.03
zafnol 50mg tablets 20s (pack size 2 x 10s)
Rs. 41.30
Rs. 43.47
eziday 25mg tablets 20s (pack size 1 x 20s)
Rs. 268.60
Rs. 282.80
co-eziday 50mg/12.5mg tablets 20s (pack size 2 x 10s)
Rs. 485.00
Rs. 510.44
labetalol hcl 50mg inj 1ampx10ml
Rs. 196.65
Rs. 207.00
co-extor 10/160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 478.38
Rs. 503.59
co-extor 5/160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 409.50
Rs. 431.06
olesta-am 5/40mg tablets 20s (pack size 2 x 10s)
Rs. 352.30
Rs. 370.80
olesta-am 5/20mg tablets 20s (pack size 2 x 10s)
Rs. 271.30
Rs. 285.55
Rs. 209.02
Rs. 220.00
Rs. 280.21
Rs. 294.98
Rs. 327.74
Rs. 345.00
Rs. 185.29
Rs. 195.02
Rs. 145.32
Rs. 152.94
Rs. 128.24
Rs. 135.00
bynevol 5mg tablets 14s (pack size 1 x 14s)
Rs. 285.04
Rs. 300.02
bynevol 2.5mg tablets 14s (pack size 1 x 14s)
Rs. 153.86
Rs. 161.98
exforge hct 10/320/25mg tablets 14s (pack size 2 x 7s)
Rs. 1,496.18
Rs. 1,574.98
arbi d 300/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 552.40
Rs. 581.45
arbi d 150/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 342.00
Rs. 360.00
arbi 150mg tablets 10s (pack size 1 x 10s)
Rs. 269.70
Rs. 283.90
avsar plus 160/10/25mg tablets 28s (pack size 4 x 7s)
Rs. 118.65
Rs. 124.89
avsar plus 160mg/10mg/12.5mg tablets 28s (pack size 4 x 7s)
Rs. 112.84
Rs. 118.75
avsar plus 160mg/5mg/25mg tablets 28s (pack size 4 x 7s)
Rs. 83.16
Rs. 87.50
avsar plus 160mg/5mg/12.5mg tablets 28s (pack size 4 x 7s)
Rs. 403.76
Rs. 425.04
telsarta a 10/80mg tablets 10s (pack size 1 x 10s)
Rs. 389.90
Rs. 410.40
telsarta a 10/40mg tablets 10s (pack size 1 x 10s)
Rs. 287.00
Rs. 302.10
telsarta a 5/40mg tablets 14s (pack size 2 x 7s)
Rs. 394.24
Rs. 415.00
sofvasc hct 10/160/25mg tablets 28s (pack size 2 x 14s)
Rs. 256.76
Rs. 270.29
sofvasc hct 10/160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 253.96
Rs. 267.26
sofvasc hct 5/160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 234.22
Rs. 246.54
telmis-a 80mg/ 5mg tablets 14s (pack size 2 x 7s)
Rs. 239.61
Rs. 252.22
telmis-a 80mg/10mg tablets 14s (pack size 2 x 7s)
Rs. 232.75
Rs. 245.00
carveda 3.125mg tablets 10s (pack size 1 x 10s)
Rs. 157.30
Rs. 165.60
triforge 5/160/12.5mg tablets 28s (pack size 4 x 7s)
Rs. 81.48
Rs. 85.75
triforge 10/160/12.5mg tablets 28s (pack size 4 x 7s)
Rs. 352.52
Rs. 371.01
triforge 10/160/25mg tablets 28s (pack size 4 x 7s)
Rs. 89.32
Rs. 94.00
nebix tablet 10mg tablets 14s (pack size 1 x 14s)
Rs. 408.38
Rs. 429.94
barilol 2.5mg tablets 14s (pack size 2 x 7s)
Rs. 26.25
Rs. 27.66
losanta 50mg tablets 20s (pack size 2 x 10s)
Rs. 171.80
Rs. 180.81
cardiolite 50mg tablets 100s (pack size 10 x 10s)
Rs. 93.90
Rs. 98.81
concor 2.5mg tablets 14s (pack size 1 x 14s)
Rs. 148.54
Rs. 156.40
sarcol 50mg tablets 20s (pack size 2 x 10s)
Rs. 233.80
Rs. 246.10
concor 5mg tablets 14s (pack size 1 x 14s)
Rs. 298.06
Rs. 313.68
sarcol-h 50/12.5mg tablets 20s (pack size 2 x 10s)
Rs. 350.80
Rs. 369.20
concor 10mg tablets 14s (pack size 1 x 14s)
Rs. 583.52
Rs. 614.28
valid 160mg tablets 14s (pack size 1 x 14s)
Rs. 344.54
Rs. 362.60
trupril 10mg tablets 14s (pack size 1 x 14s)
Rs. 175.00
Rs. 184.24
m-low 5mg tablets 20s (pack size 2 x 10s)
Rs. 152.00
Rs. 160.00
m-low 10mg tablets 20s (pack size 2 x 10s)
Rs. 76.00
Rs. 80.00
corbis 5mg tablets 20s (pack size 2 x 10s)
Rs. 211.80
Rs. 223.00
co-trupril 20/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 340.62
Rs. 358.54
valmo 10/160mg tablets 14s (pack size 1x14s)
Rs. 627.34
Rs. 660.39
lodopin 5mg tablets 20s (pack size 2 x 10s)
Rs. 78.10
Rs. 82.20
lodopin 2.5mg tablets 20s (pack size 2 x 10s)
Rs. 59.90
Rs. 63.00
lodopin 10mg tablets 20s (pack size 2 x 10s)
Rs. 103.60
Rs. 109.00
capoten 25mg tablets 20s (pack size 2 x 10s)
Rs. 152.00
Rs. 159.99
exforge hct 5/160/25mg tablets 14s (pack size 2 x 7s)
Rs. 1,018.36
Rs. 1,072.00
exforge hct 10/160/12.5mg tablets 14s (pack size 2 x 7s)
Rs. 1,533.98
Rs. 1,614.65
lamoretic 20/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 313.46
Rs. 330.00
co-baritec 20/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 237.50
Rs. 250.00
exforge hct 5/160/12.5mg tablets 14s (pack size 2 x 7s)
Rs. 1,428.14
Rs. 1,503.27
co-valtec 160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 375.76
Rs. 395.50
sofvasc-v 10/160mg tablets 14s (pack size 1 x 14s)
Rs. 713.58
Rs. 751.11
xavor diu 50/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 260.90
Rs. 274.62
co-valtec 80/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 252.70
Rs. 266.00
exforge hct 10/160/25mg tablets 14s (pack size 2 x 7s)
Rs. 1,094.10
Rs. 1,151.64
irecon-h 150/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 294.50
Rs. 310.00
betaloc zok 100mg tablets 30s (pack size 3 x 10s)
Rs. 969.00
Rs. 1,020.00
co-tasmi 80/12.5mg tablets 14s (pack size 2 x 7s)
Rs. 289.73
Rs. 304.99
telsarta d 40/12.5mg tablets 14s (pack size 2 x 7s)
Rs. 394.24
Rs. 414.96
natrilix sr 1.5mg tablets 30s (pack size 2 x 15s)
Rs. 222.45
Rs. 234.15
co-tasmi 40/12.5mg tablets 14s (pack size 2 x 7s)
Rs. 204.26
Rs. 215.00
diu-tansin 50/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 188.10
Rs. 197.98
co-aprovel 150/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 648.48
Rs. 682.63
co-olesta 20/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 234.70
Rs. 247.00
sofvasc-v 5/160mg tablets 14s (pack size 1 x 14s)
Rs. 608.02
Rs. 640.08
co-valtec 160/25mg tablets 28s (pack size 2 x 14s)
Rs. 330.68
Rs. 348.04
co-diovan 160/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 2,037.84
Rs. 2,145.11
coversyl plus 4/1.25mg tablets 10s (pack size 1 x 10s)
Rs. 447.50
Rs. 471.07
zestoretic 20/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 610.54
Rs. 642.74
sartan-h 50/12.5mg tablets 10s (pack size 1 x 10s)
Rs. 264.10
Rs. 278.00
co-diovan 80/12.5mg tablets 28s (pack size 2 x 14s)
Rs. 1,222.76
Rs. 1,287.07
dioplus 10/160mg tablets 14s (pack size 2 x 7s)
Rs. 617.54
Rs. 650.00
losar -k 50mg tablets 20s (pack size 2 x 10s)
Rs. 190.00
Rs. 200.00
co-a2a 50/12.5mg tablets 20s (pack size 2 x 10s)
Rs. 243.90
Rs. 256.70
newday 10/160mg tablets 14s (pack size 1 x 14s)
Rs. 412.30
Rs. 434.00
co-diovan 160/25mg tablets 28s (pack size 2 x 14s)
Rs. 2,057.72
Rs. 2,166.07
ramipace 1.25mg tablets 28s (pack size 2 x 14s)
Rs. 162.40
Rs. 171.00
telmis-a 5/40mg tablets 14s (pack size 1 x 14s)
Rs. 359.10
Rs. 378.00
exforge 10/160mg tablets 28s (pack size 2 x 14s)
Rs. 3,356.92
Rs. 3,533.60
sofvasc-v 5/80mg tablets 14s (pack size 1 x 14s)
Rs. 425.32
Rs. 447.71
dioplus 5/80mg tablets 14s (pack size 2 x 7s)
Rs. 373.94
Rs. 393.63
omsana am 10/20mg tablets 20s (pack size 2 x 10s)
Rs. 266.00
Rs. 280.00
coversam 4/10mg tablets 10s (pack size 1 x 10s)
Rs. 432.00
Rs. 454.71
renitec 10mg tablets 20s (pack size 2 x 10s)
Rs. 146.90
Rs. 154.60
Rs. 610.80
Rs. 643.00
vedicar 6.25mg tablets 30s (pack size 3 x 10s)
Rs. 88.70
Rs. 93.33
aldactone 100mg tablets 10s (pack size 1 x 10s)
Rs. 110.20
Rs. 116.05
aldomet 250mg tablets 100s (pack size 10 x 10s)
Rs. 116.40
Rs. 122.51
exforge 5/160mg tablets 28s (pack size 2 x 14s)
Rs. 2,313.92
Rs. 2,435.73
dioplus 5/160mg tablets 14s (pack size 2 x 7s)
Rs. 534.66
Rs. 562.80
omsana am 5/40mg tablets 20s (pack size 2 x 10s)
Rs. 442.20
Rs. 465.50
aprovel 300mg tablets 28s (pack size 2 x 14s)
Rs. 3,539.76
Rs. 3,726.12
omsana am 5/20mg tablets 20s (pack size 2 x 10s)
Rs. 333.50
Rs. 351.00
am-telsan 5/80mg tablets 14s (pack size 2 x 7s)
Rs. 592.76
Rs. 624.00
am-telsan 5/40mg tablets 14s (pack size 2 x 7s)
Rs. 467.46
Rs. 492.00
exforge 5/80mg tablets 28s (pack size 2 x 14s)
Rs. 1,008.56
Rs. 1,061.58
valtec 160mg tablets 28s (pack size 2 x 14s)
Rs. 306.88
Rs. 323.00
vedicar 12.5mg tablets 10s (pack size 1 x 10s)
Rs. 142.50
Rs. 150.00
tenoret 50mg tablets 14s (pack size 1 x 14s)
Rs. 183.68
Rs. 193.34
carveda 12.5mg tablets 30s (pack size 3 x 10s)
Rs. 179.80
Rs. 189.30
coversam 8/5mg tablets 10s (pack size 1 x 10s)
Rs. 393.80
Rs. 414.51
coversam 4/5mg tablets 10s (pack size 1 x 10s)
Rs. 389.60
Rs. 410.13
bosmon 62.5mg tablets 14s (pack size 2 x 7s)
Rs. 883.47
Rs. 930.00
valam 10/160mg tablets 14s (pack size 2 x 7s)
Rs. 308.49
Rs. 324.74
extor 10/160mg tablets 14s (pack size 1 x 14s)
Rs. 490.98
Rs. 516.80
Rs. 222.00
Rs. 233.69
avsar 160/10mg tablets 14s (pack size 2 x 7s)
Rs. 570.08
Rs. 600.04
extor 5/160mg tablets 14s (pack size 1 x 14s)
Rs. 411.04
Rs. 432.60
norvasc 10mg tablets 30s (pack size 3 x 10s)
Rs. 932.40
Rs. 981.60
cardaxen 50mg tablets 20s (pack size 2 x 10s)
Rs. 69.40
Rs. 73.00
byscard 2.5mg tablets 14s (pack size 1 x 14s)
Rs. 152.18
Rs. 160.21
tritace 2.5mg tablets 28s (pack size 2 x 14s)
Rs. 292.60
Rs. 308.00
telsarta 80mg tablets 10s (pack size 1 x 10s)
Rs. 345.30
Rs. 363.52
telsarta 40mg tablets 10s (pack size 1 x 10s)
Rs. 237.50
Rs. 250.00
ramipace 10mg tablets 28s (pack size 2 x 14s)
Rs. 377.58
Rs. 397.46
newday 5/80mg tablets 14s (pack size 1 x 14s)
Rs. 316.40
Rs. 333.00
avsar 160/5mg tablets 14s (pack size 2 x 7s)
Rs. 469.42
Rs. 494.06
monitor 2.5mg tablets 14s (pack size 1 x 14s)
Rs. 59.92
Rs. 63.00
norvasc 5mg tablets 30s (pack size 3 x 10s)
Rs. 476.70
Rs. 501.84
coversyl 8mg tablets 10s (pack size 1 x 10s)
Rs. 396.20
Rs. 417.00
coversyl 2mg tablets 10s (pack size 1 x 10s)
Rs. 208.30
Rs. 219.29
coversyl 4mg tablets 10s (pack size 1 x 10s)
Rs. 395.20
Rs. 416.05
valam 5/160mg tablets 14s (pack size 2 x 7s)
Rs. 262.92
Rs. 276.78
ampress 5mg tablets 20s (pack size 2 x 10s)
Rs. 95.00
Rs. 100.00
extor 5/80mg tablets 14s (pack size 1 x 14s)
Rs. 332.50
Rs. 350.00
blokium 50mg tablets 30s (pack size 3 x 10s)
Rs. 98.80
Rs. 104.00
carveda 25mg tablets 10s (pack size 1 x 10s)
Rs. 328.70
Rs. 346.00
treatan 16mg tablets 28s (pack size 2 x 14s)
Rs. 898.80
Rs. 946.20
baritec 40mg tablets 10s (pack size 1 x 10s)
Rs. 323.00
Rs. 340.00
ramipace 5mg tablets 28s (pack size 2 x 14s)
Rs. 303.94
Rs. 320.00
zestril 20mg tablets 14s (pack size 1 x 14s)
Rs. 710.50
Rs. 747.88
zestril 10mg tablets 14s (pack size 1 x 14s)
Rs. 369.60
Rs. 389.00
monitor 5mg tablets 14s (pack size 1 x 14s)
Rs. 209.02
Rs. 220.00