Ceporex 250Mg/5Ml Suspension 90Ml
Brand : glaxo smith kline pakistan
Per pc
Rs. 227.41
Rs. 239.38
How it works
Cephalexin is an oral broad-spectrum antibiotic. In adequate concentrations it is bactericidal for sensitive proliferating microorganisms by inhibiting the biosynthesis of the cell wall.
Description
CEPOREX 250MG/5ML SYP 90ML
Generics
Cephalexin
used for
Bacterial Infection
Requires Prescription (YES/NO)
Yes
Indication
It is indicated for treatment of respiratory tract infections (RTIs), urinary tract infections (UTIs), skin and soft tissue infections, otitis media and other infections due to sensitive organisms.
Side Effects
Nausea, vomiting, diarrhoea and abdominal discomfort , Dyspepsia , Transient hepatitis and cholestatic jaundice , rash, urticaria, angioedema and rarely erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis (exanthematic necrolysis) , genital and anal pruritus, genital candidiasis, vaginitis and vaginal discharge, dizziness, fatigue, headache, agitation, confusion, hallucinations, arthralgia, arthritis and joint disorders, Eosinophilia, neutropenia, thrombocytopenia, haemolytic anaemia and slight elevations in AST and ALT.
When not to Use
Cephalexin is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Severe systemic infections, which require parenteral cephalosporin treatment, should not be treated orally during the acute stage.
Dosage
Adults: The dosage is 1- 4 g daily in divided doses. Most infections will respond to 500 mg every 8 hours. For skin and soft tissue infections, streptococcal pharyngitis and mild uncomplicated UTIs, the usual dosage is 250 mg every 6 hours or 500 mg every 12 hours. For more severe infections or those caused by less susceptible organisms, larger doses may be needed. Children: The usual recommended daily dosage for children is 25-50mg/kg in divided doses. For skin and soft tissue infections, streptococcal pharyngitis and mild, uncomplicated urinary tract infections, the total daily dose may be divided and administered every 12 hours. For most infections the following schedule is suggested: children under 5 years - 125 mg every 8 hours ; children 5 years and over - 250 mg every 8 hours In severe infections the dosage may be doubled. In the therapy of otitis media, clinical studies have shown that a dosage of 75- 100mg/kg/day in 4 divided doses is required. In the treatment of betahaemolytic streptococcal infections, a therapeutic dose should be administered for at least 10 days. Always consult your doctor or pharmacist for dose adjustments.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Precautions
Cephalosporins should be given with caution to penicillin-sensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and cephalosporins. Patients have had severe reactions (including anaphylaxis) to both drugs.
Warning 1
Prolonged use of cephalexin may result in the overgrowth of non-susceptible organisms. Careful observation of the patient is essential. If superinfection occurs during therapy, appropriate measures should be taken.
Warning 2
Cephalexin should be administered with caution in the presence of markedly impaired renal function as it is excreted mainly by the kidneys. Careful clinical and laboratory studies should be made because the safe dosage may be lower than that usually recommended.
Warning 3
Cephalexin is excreted in human milk in low concentrations and should be used with caution in nursing mothers.
Pregnancy category
Always consult your physician before using any medicine.
Drug Interactions
Bacteriostatic antibiotics , Uricosuric drugs (e.g. probenecid) , Metformin , ethacrynic acid, furosemide , aminoglycosides, polymyxin, colistin , Oral anticoagulants , Typhoid vaccine , Oral contraceptives , Cytotoxic drugs .
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