Cis-Curon Iv Specification
Requires Prescription (YES/NO)
Yes
Generics
Cis-atracurium Besylate
Used For
Anesthesia
How it works
Cisatracurium, a stereoisomer of atracurium, is an intermediate duration, non-depolarising benzylisoquinolinium skeletal muscle relaxant. Cisatracurium besylate binds to cholinergic receptors on the motor end-plate to antagonise the action of acetylcholine, resulting in a competitive block of neuromuscular transmission. This action is readily reversed by anticholinesterase agents such as neostigmine.
Cis-Curon Iv Usage And Safety
Dosage
Cis-atracurium Besylate
Side Effects
Cardiovascular : Bradycardia (0.4%), hypotension (0.2%), flushing (0.2%). Respiratory : Bronchospasm (0.2%). Dermatological: Rash (0.1%). Hypersensitivity : Very rarely : Severe anaphylactic reactions have been reported in patients receiving Cis-Curon Injection in conjunction with one or more anaesthetic agents.
Drug Interactions
Enflurane , isoflurane , halothane , ketamine , aminoglycosides , polymyxin , spectinomycin , tetracyclines , linomycin , clindamycin , propranolol calcium-channel blockers , lignocaine , procaineamide , quninidine , furosemide , thiazides , mannitol , acetazolamide , phenytoin , carbamazepine .
Indication
As an adjunct to general anaesthesia. To facilitate non-emergency endotracheal intubation . To provide skeletal muscle relaxation during surgery or mechanical ventilation.
When not to Use
Cis-atracurium Besylate Injection is contraindicated in patients known to be hypersensitive to cisatracurium besylate, atracurium besylate or benzenesulfonic acid .
Cis-Curon Iv Precautions
Precaution
It is essential to maintain pulmonary ventilation and arterial oxygenation until adequate spontaneous respiration returns.
Cis-Curon Iv Warnings
Warning 1
Prolonged muscle paralysis and its consequences are expected to be the main signs of overdose with Cis-atracurium Besylate Injection.
Warning 2
Full sedation will be required since consciousness is not impaired by Cis-atracurium Besylate Injection .
Warning 3
Recovery may be accelerated by the administration of anticholinesterase agents once evidence of spontaneous recovery is present.
Cis-Curon Iv Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store in a refrigerator (2°C–8°C). Do not Freeze .