SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Eszopiclone
Used For
Insomnia
How it works
The precise mechanism of action of eszopiclone as a hypnotic is unknown, but its effect is believed to result from its interaction with GABA-receptor complexes at binding domains located close to or allosterically coupled to benzodiazepine receptors. Eszopiclone is a nonbenzodiazepine hypnotic that is a pyrrolopyrazine derivative of the cyclopyrrolone class with a chemical structure unrelated to pyrazolopyrimidines, imidazopyridines, benzodiazepines, barbiturates, or other drugs with known hypnotic properties.
USAGE AND SAFETY
Dosage
Eszopiclone
Side Effects
Headache , Viral Infection , Dry Mouth , Dyspepsia , Nausea , Vomiting , Anxiety , Confusion , Depression , Dizziness , Hallucinations , Libido Decreased , Nervousness , Somnolence , Infection , Rash , Unpleasant Taste
Drug Interactions
Ethanol , Paroxetine , Lorazepam , Olanzapine , Drugs That Inhibit CYP3A4 (Ketoconazole) , Drugs That Induce CYP3A4 (Rifampicin) , Drugs Highly Bound To Plasma Protein , Drugs With A Narrow Therapeutic Index
Indication
It is indicated for the treatment of insomnia .
When not to Use
Hypersensitive to any of the ingredients in the list.
PRECAUTIONS
Precaution
It should be taken immediately before bedtime. Taking a sedative/hypnotic while still up and about may result in short-term memory impairment, hallucinations, impaired coordination, dizziness, and light headedness.
WARNINGS
Warning 1
Because sleep disturbances may be the presenting manifestation of a physical and/or psychiatric disorder, symptomatic treatment of insomnia should be initiated only after a careful evaluation of the patient.
Warning 2
Rare cases of angioedema involving the tongue, glottis or larynx have been reported in patients after taking the first or subsequent doses of sedative-hypnotics, including this medicine. Some patients have had additional symptoms such as dyspnea, throat closing, or nausea and vomiting that suggest anaphylaxis. Some patients have required medical therapy in the emergency department. If angioedema involves the tongue, glottis or larynx, airway obstruction may occur and be fatal. Patients who develop angioedema after treatment with this medicine should not be rechallenged with the drug.
Warning 3
Clinical experience with eszopiclone in patients with concomitant illness is limited. Eszopiclone should be used with caution in patients with diseases or conditions that could affect metabolism or hemodynamic responses.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.