Uses : It Is used for conditions that affect the heart such as heart failure, chest pain, and high blood pressure. It is also used for preventing migraine headache, parkinson’s disease, and many other conditions. Side effects : It can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, And diarrhea. Interaction : Hypersensitivity to the drug. People with chronic diseases such As heart Failure, kidney Or liver Problems, or diabetes should be aware of using this Supplement. CoQ10 May lower blood sugar levels and blood Pressure. Doses of more than 300 milligrams may affect liver enzyme levels . Precautions : People taking blood thinners and thyroid medications as well as chemotherapy should check with their doctors before using coQ10 supplements .Coenzyme Q-10 Is an antioxidant. There Is some concern that antioxidants might decrease the effectiveness of some medications used for cancers but it is too soon to know if the interaction occurs. Some medications for high blood pressure include captopril (capoten), enalapril (vasotec), losartan (cozaar), valsartan (diovan), diltiazem (cardizem), amlodipine (norvasc), hydrochlorothiazide (hydroDiuril), furosemide (lasix), and many others.