Darbazine Injection 200Mg (1 Box = 1 Injection)

Name: Darbazine Injection 200Mg (1 Box = 1 Injection)
Brand: PHARMADIC
Price: 475

Brand : pharmadic

Rs. 475.00

Rs. 500.00

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Darbazine Injection Specification

Requires Prescription (YES/NO)

Yes

Generics

Dacarbazine

Used For

Cancer

How it works

Dacarbazine belongs to the group of medicines known as cytostatic agents. These agents influence the growth of cancer cells.

Darbazine Injection Usage And Safety

Dosage

Dacarbazine

Side Effects

Common (may affect up to1 in 10 people) : • Decreased number of red blood cells (anaemia) • Decreased number of white blood cells (leukopenia) • Decreased number of platelets in the blood (thrombocytopenia) • Loss of appetite (anorexia), feeling sick and being sick (all of which may be severe) ; Uncommon (may affect up to 1 in 100 people) : • Hair loss (alopecia) • Increased skin colouring (hyperpigmentation) • Sensitivity to light (photosensitivity) of the skin • Flu-like symptoms with exhaustion, chills, fever and muscular pain. • Infections ; Rare (may affect up to 1 in 1,000 people) : • Decreased number of all cells in the blood (pancytopenia) • Severely decreased number of granulocytes, a special type of white blood cells (agranulocytosis) • Severe allergic (anaphylactic) reaction resulting in e.g. drop in blood pressure, swelling of the hands, feet, ankles, face, lips, mouth and throat which may cause difficulty in swallowing or breathing, rapid pulse, hives and generalised itching or skin redness • Headaches • Impaired vision • Confusion

Drug Interactions

Phenytoin , Methoxypsoralen , Cyclosporine or tacrolimus , Fotemustine , diazepam , imipramine , ketoconazole , carbamazepine , Anticoagulants , Radiation treatment .

Indication

Dacarbazine for Injection is indicated in the treatment of metastatic malignant melanoma. In addition, Dacarbazine for Injection is also indicated for Hodgkin's disease as a second-line therapy when used in combination with other effective agents.

When not to Use

Dacarbazine for Injection is contraindicated in patients who have demonstrated a hypersensitivity to it in the past.

Darbazine Injection Precautions

Precaution

Hospitalization is not always necessary but adequate laboratory study capability must be available. Extravasation of the drug subcutaneously during intravenous administration may result in tissue damage and severe pain. Local pain, burning sensation and irritation at the site of injection may be relieved by locally applied hot packs.

Darbazine Injection Warnings

Warning 1

Hemopoietic depression is the most common toxicity with Dacarbazine for Injection and involves primarily the leukocytes and platelets, although, anemia may sometimes occur.

Warning 2

Hepatic toxicity accompanied by hepatic vein thrombosis and hepatocellular necrosis resulting in death, has been reported.

Warning 3

Anaphylaxis can occur following the administration of Dacarbazine for Injection .

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