Ernem Inj 1 Gm 1 Vial

Brand : genix pharma private limited

Rs. 5,350.21

Rs. 5,631.80

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Ernem Inj Specification

Requires Prescription (YES/NO)

Yes

Generics

Ertapenem Sodium

Used For

Bacterial Infection

How it works

Ertapenem inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). In Escherichia coli, affinity is strongest to PBPs 2 and 3.

Ernem Inj Usage And Safety

Dosage

Ertapenem Sodium

Side Effects

Headache • Diarrhoea, nausea, vomiting • Rash, itching • Problems with the vein into which the medicine is given (including inflammation, formation of a lump, swelling at the injection site, or leaking of fluid into the tissue and skin around the injection site) • Increase in platelet count • Changes in liver function tests • Dizziness, sleepiness, sleeplessness, confusion, seizure • Low blood pressure, slow heart rate • Shortness of breath, sore throat • Constipation, yeast infection of the mouth, antibiotic-associated diarrhoea, acid regurgitation, dry mouth, indigestion, loss of appetite • Skin redness

Drug Interactions

Tell your doctor, nurse or pharmacist if you are taking medicines called valproic acid or sodium valproate (used to treat epilepsy, bipolar disorder, migraines, or schizophrenia). This is because Ertapenem Sodium can affect the way some other medicines work. Your doctor will decide whether you should use Ertapenem Sodium in combination with these other medicines.

Indication

It is indicated in paediatric patients (3 months to 17 years of age) and in adults for the treatment of the following infections when caused by bacteria known or very likely to be susceptible to ertapenem and when parenteral therapy is required : Intra-abdominal infections ; Community acquired pneumonia ; Acute gynaecological infections ; Diabetic foot infections of the skin and soft tissue .

When not to Use

Hypersensitivity to the active substance or to any of the excipients ; Hypersensitivity to any other carbapenem antibacterial agent ; Severe hypersensitivity (e.g., anaphylactic reaction, severe skin reaction) to any other type of beta-lactam antibacterial agent (e.g., penicillins or cephalosporins).

Ernem Inj Precautions

Precaution

Encephalopathy has been reported with the use of ertapenem . If ertapenem-induced encephalopathy is suspected (e.g. myoclonus, seizures, altered mental status, depressed level of consciousness), discontinuation of ertapenem should be considered. Patients with renal impairment are at higher risk of ertapenem-induced encephalopathy and the resolution may be prolonged.

Ernem Inj Warnings

Warning 1

Before initiating therapy with ertapenem, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, other beta-lactams and other allergens . If an allergic reaction to ertapenem occurs , discontinue the therapy immediately. Serious anaphylactic reactions require immediate emergency treatment.

Warning 2

Prolonged use of ertapenem may result in overgrowth of non-susceptible organisms. Repeated evaluation of the patient's condition is essential. If superinfection occurs during therapy, appropriate measures should be taken.

Warning 3

Antibiotic-associated colitis and pseudomembranous colitis have been reported with ertapenem and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhoea subsequent to the administration of antibacterial agents. Discontinuation of therapy with Ertapenem Sodium and the administration of specific treatment for Clostridioides difficile should be considered. Medicinal products that inhibit peristalsis should not be given.