Hiramox Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Moxifloxacin HCl
Used For
Bacterial Infection
How it works
Moxifloxacin has in vitro activity against a wide range of Gram-positive and Gram-negative microorganisms. The bactericidal action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair, and recombination. It appears that the C8-methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of Gram-positive bacteria compared to the C8-H moiety. The presence of the bulky bicycloamine substituent at the C 7 position prevents active efflux, associated with the NorA or pmrA genes seen in certain Gram-positive bacteria.
Hiramox Tablets Usage And Safety
Dosage
Moxifloxacin HCl
Side Effects
BODY AS A WHOLE: Abdominal pain, headache, asthenia, injection site reaction (including phlebitis), malaise, moniliasis, pain, allergic reaction CARDIOVASCULAR: Tachycardia, palpitation, vasodilation, QT interval prolonged DIGESTIVE: Vomiting, abnormal liver function test, dyspepsia, dry mouth, flatulence, oral moniliasis, constipation, GGTP increased, anorexia, stomatitis, glossitis HEMIC AND LYMPHATIC: Leukopenia, eosinophilia, prothrombin decrease (prothrombin time prolonged/International Normalized Ratio (INR) increased), thrombocythemia METABOLIC AND NUTRITIONAL: Lactic dehydrogenase increased, amylase increased MUSCULOSKELETAL: Arthralgia, myalgia NERVOUS SYSTEM: Insomnia, nervousness, vertigo, somnolence, anxiety, tremor SKIN/APPENDAGES: Rash (maculopapular, purpuric, pustular), pruritus, sweating, urticaria SPECIAL SENSES: Taste perversion.
Drug Interactions
Drugs that prolong the QT interval including antiarrhythmics , antipsychotics , neuroleptics , TCADS , antimicrobials , antihistamins , cisapride. Corticosteroids , hypokalaemic agents , anticoagulants, Antacids , didanosine , sucralfate , charcoal , iron or zinc supplements.
Indication
It is indicated for the treatment of adults (> 18 years of age) with infections caused by susceptible strains of the designated microorganisms in the conditions listed below:Acute Bacterial Sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis. Acute Bacterial Exacerbation of Chronic Bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus, or Moraxella catarrhalis.Community Acquired Pneumonia caused by Streptococcus pneumoniae.
When not to Use
Moxifloxacin is contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antimicrobial agents.
Hiramox Tablets Precautions
Precaution
Quinolones may cause central nervous system (CNS) events, including: nervousness, agitation, insomnia, anxiety, nightmares or paranoia.
Hiramox Tablets Warnings
Warning 1
Moxifloxacin has been shown to prolong the QT interval of the electrocardiogram in some patients. The drug should be avoided in patients with known prolongation of the QT interval, patients with uncorrected hypokalemia and patients receiving Class IA (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic agents, due to the lack of clinical experience with the drug in these patient populations.
Warning 2
Moxifloxacin should be used with caution in patients with ongoing proarrhythmic conditions, such as clinically significant bradycardia, acute myocardial ischemia. The magnitude of QT prolongation may increase with increasing concentrations of the drug or increasing rates of infusion of the intravenous formulation. Therefore the recommended dose or infusion rate should not be exceeded.
Warning 3
Convulsions have been reported in patients receiving quinolones. Quinolones may also cause central nervous system (CNS) events including: dizziness, confusion, tremors, hallucinations, depression and rarely, suicidal thoughts or acts. These reactions may occur following the first dose. If these reactions occur in patients receiving moxifloxacin, the drug should be discontinued and appropriate measures instituted.
Hiramox Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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ecasil tablets 600mg (1 strip = 6 tablets)
Rs. 837.78
Rs. 881.90
ecasil tablets 400mg (1 strip = 6 tablets)
Rs. 520.14
Rs. 547.50
caricef capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 513.00
Rs. 540.00
oflobid tablets 400mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 355.10
Rs. 373.74
inoquin tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 218.50
Rs. 230.00
oflobid tablets 200mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 347.70
Rs. 366.00
cefstar iv/im injection 1000mg (1 box = 1 injection)
Rs. 883.50
Rs. 930.00
cefim 30ml suspension 100mg/5ml
Rs. 279.54
Rs. 294.25
Rs. 275.50
Rs. 290.00
cefiget tablets 200mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 544.40
Rs. 573.00
tanzo iv injection 4.5g (1 box = 1 injection)
Rs. 1,134.30
Rs. 1,194.00
rifaxa tablets 550mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 978.50
Rs. 1,030.00
rifaxa tablets 200mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 408.50
Rs. 430.00
cefspan capsules 400mg (1 bottle = 5 capsules)
Rs. 665.00
Rs. 700.00
barimox tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 494.00
Rs. 520.00
cedrox tablets 1g (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 545.80
Rs. 574.50
zetamax tablets 250mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 292.02
Rs. 307.38
evofix capsules 400mg (1 box = 1 strip)(1 strip = 10 capsules)
Rs. 703.00
Rs. 740.00
entamizole ds tablets 500mg/400mg (1 box = 15 tablets)
Rs. 229.95
Rs. 242.00
mofest tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 498.75
Rs. 525.00
hiflox tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 380.00
Rs. 400.00
nimixa tablets 550mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 1,076.40
Rs. 1,133.00
moxiget tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 564.30
Rs. 594.00
cravit tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 1,407.90
Rs. 1,481.96
leflox tablets 750mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 655.50
Rs. 690.00
leflox tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 508.30
Rs. 535.00
cravit tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 710.30
Rs. 747.69
leflox tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 311.60
Rs. 328.00
vinjec iv injection 1g (1 box = 1 injection)
Rs. 1,870.55
Rs. 1,969.00
prelox tablets 100mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 380.00
Rs. 400.00
q-bact im/iv injection 2g (1 box = 1 injection)
Rs. 707.77
Rs. 745.02
q-bact im/iv injection 1g (1 box = 1 injection)
Rs. 498.75
Rs. 525.00
cebosh tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 465.50
Rs. 490.00
cebosh capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 465.50
Rs. 490.00
cefiget capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 465.70
Rs. 490.20
cebac im/iv injection 2g (1 box = 1 injection)
Rs. 593.75
Rs. 625.00
cebac im/iv injection 1g (1 box = 1 injection)
Rs. 451.25
Rs. 475.00
hizone iv injection 1g (1 box = 1 injection)
Rs. 608.00
Rs. 640.00
cebosh tablets 200mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 494.00
Rs. 520.00
calamox tablets 625mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 214.50
Rs. 225.76
calamox tablets 375mg (1 box = 1 strip) (1 strip = 6 tablets)
Rs. 164.70
Rs. 173.34
avelox tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 1,283.35
Rs. 1,350.88
azotek tablets 250mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 232.74
Rs. 245.00
azotek tablets 500mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 436.98
Rs. 460.00
meflox tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 565.25
Rs. 595.01
calamox tablets 1g (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 271.56
Rs. 285.84
cycin tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 437.00
Rs. 460.00
cycin tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 247.00
Rs. 260.00
Rs. 869.82
Rs. 915.55
prevent tablets 1g (1 strip = 10 tablets)
Rs. 173.10
Rs. 182.25
qumic tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 427.50
Rs. 450.00
qumic tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 266.00
Rs. 280.00
penro iv injection 1000mg (1 box = 1 injection)
Rs. 3,184.40
Rs. 3,352.00
2sum im/iv injection 2g (1 box = 1 injection)
Rs. 560.50
Rs. 590.00
zetro capsules 250mg (1 box = 1 strip)(1 strip = 10 capsules)
Rs. 468.70
Rs. 493.32
grat tablets 320mg (1 box = 1 strip)(1 strip = 7 tablets)
Rs. 997.50
Rs. 1,050.00
entamizole 90ml suspension 250mg/200mg
Rs. 128.25
Rs. 135.00
plazo tablets 500mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 403.74
Rs. 425.00
cefim capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 484.50
Rs. 510.00
lcyn tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 437.00
Rs. 460.00
lcyn tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 304.00
Rs. 320.00
evofix 30ml suspension 100mg/5ml
Rs. 270.75
Rs. 285.00
metrozine 90ml suspension 200mg/5ml
Rs. 87.02
Rs. 91.60
moksi tablets 400mg (1 box = 1 strip)(1 strip = 5 tablets)
Rs. 741.00
Rs. 780.00
zezot capsules 250mg (1 box = 1 strip)(1 strip = 6 capsules)
Rs. 204.48
Rs. 215.26
Rs. 333.76
Rs. 351.33
mixel capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 551.10
Rs. 580.08
mixel capsules 200mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 288.65
Rs. 303.85
zinacef im/iv injection 750mg (1 box = 1 injection)
Rs. 252.07
Rs. 265.34
aziscot tablets 500mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 342.00
Rs. 360.00
aziscot 30ml suspension 200mg/5ml
Rs. 361.00
Rs. 380.00
zinacef iv/im injection 250mg (1 box = 1 injection)
Rs. 82.92
Rs. 87.28
bi-cip tablets 250mg (1 box = 10 tablets)
Rs. 190.00
Rs. 200.00
rifazin tablets 550mg (1 box = 10 tablets)
Rs. 1,140.00
Rs. 1,200.00
Rs. 265.32
Rs. 279.29
ticozid im/iv injection 200mg (1 box = 1 injection)
Rs. 1,515.25
Rs. 1,595.00
ticozid im/iv injection 400mg (1 box = 1 injection)
Rs. 2,370.25
Rs. 2,495.00
zyto 15ml suspension 200mg/5ml
Rs. 283.10
Rs. 298.00
zyto tablets 500mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 487.74
Rs. 513.43
zyto tablets 250mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 336.48
Rs. 354.20
meroget iv injection 1g (1 box = 1 injection)
Rs. 3,220.43
Rs. 3,389.93
tucana capsules 400mg (1 box = 5 capsules)
Rs. 88.37
Rs. 93.02
dayzone iv injection 1g (1 box = 1 injection)
Rs. 437.00
Rs. 460.00
zetro 25ml suspension 200mg/5ml
Rs. 445.92
Rs. 469.39
maxithro tablets 250mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 245.46
Rs. 258.35
axcin tablets 250mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 199.50
Rs. 210.00
zolrest 300ml infusion 600mg/300ml (1 box = 1 infusion)
Rs. 878.75
Rs. 925.00
nezkil 300ml infusion 600mg (1 box = 1 infusion)
Rs. 807.50
Rs. 850.00
atizor 30ml suspension 200mg/5ml
Rs. 361.00
Rs. 380.00
tazbac iv injection 4.5g (1 box = 1 injection)
Rs. 1,256.84
Rs. 1,322.99
olver iv injection 1g (1 box = 1 injection)
Rs. 2,683.28
Rs. 2,824.50
olver iv injection 500mg (1 box = 1 injection)
Rs. 1,416.45
Rs. 1,491.00
zetro tablets 500mg (1 box = 2 strips) (1 strip = 3 tablets)
Rs. 480.72
Rs. 506.00
Rs. 169.20
Rs. 178.05
ospamox tablets 1000mg (1 box = 2 strips) (1 strip = 6 tablets)
Rs. 356.04
Rs. 374.75
linzo tablets 400mg (1 box = 2 strips) (1 strip = 6 tablets)
Rs. 1,387.08
Rs. 1,460.04
prevent tablets 500mg (1 box = 5 strips) (1 strip = 10 tablets)
Rs. 120.40
Rs. 126.70
vancotic iv injection 1g (1 box = 1 injection)
Rs. 1,689.04
Rs. 1,777.94
amoxi-clav tablets 375mg (1 box = 2 strips) (1 strip = 3 tablets)
Rs. 164.70
Rs. 173.34
augmentin bd tablets 1000mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 344.40
Rs. 362.54
augmentin tablets 625mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 265.08
Rs. 279.00
augmentin tablets 375mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 255.48
Rs. 268.92
maxithro tablets 500mg (1 box = 1 strip)(1 strip = 6 tablets)
Rs. 450.00
Rs. 473.67
iboxime ds 30ml suspension 200mg/5ml
Rs. 327.75
Rs. 345.00
cipnesss tablets 250mg (1 box = 1 strip) (1 strip = 10 tablets)
Rs. 209.00
Rs. 220.00
vinzat injection 2.5g (1 box = 1 injection)
Rs. 497.76
Rs. 523.96
cipness tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 342.00
Rs. 360.00
em-flox tablets 400mg (1 box = 1 strip) (1 strip = 5 tablets)
Rs. 627.00
Rs. 660.00
iboxime capsules 400mg (1 box = 1 strip)(1 strip = 5 capsules)
Rs. 513.00
Rs. 540.00
lcyn tablets 750mg (1 box = 1 strip)(1 strip = 10 tablets)
Rs. 627.00
Rs. 660.00
klaricid 60ml suspension 125mg/5ml
Rs. 532.95
Rs. 561.00
sionex-bd tablets 500mg (1 box = 2 strips) (1 strip = 6 tablets)
Rs. 387.60
Rs. 408.00
barizold 60ml dry suspension 100mg/5ml
Rs. 451.25
Rs. 475.00
azomax 500 capsules 500mg (1 box = 2 strips) (1 strip = 3 capsules)
Rs. 505.38
Rs. 532.00
azomax 250 capsules 250mg (1 box = 2 strips) (1 strip = 6 capsules)
Rs. 731.52
Rs. 770.00
klaricid ds 60ml suspension 250/5ml
Rs. 887.78
Rs. 934.50
cefim capsules 200mg (1 box = 1 strip)(1 strip = 10 capsules)
Rs. 569.20
Rs. 599.20
mixel 30ml suspension 100mg/5ml
Rs. 304.95
Rs. 321.00
augmentin bd 35ml suspension 457mg/5ml
Rs. 190.12
Rs. 200.13
rithmo 25ml oral drops 125mg/5ml
Rs. 180.26
Rs. 189.75
abacus 50ml suspension 40mg/5ml
Rs. 380.00
Rs. 400.00