Izato Tablet 500Mg (1 Strip = 5 Tablets)

Name: Izato Tablet 500Mg (1 Strip = 5 Tablets)
Brand: SAMI PHARM (PVT) LTD.
Price: 356.30

Brand : sami pharm (pvt) ltd.

Rs. 356.30

Rs. 375.00

|

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Izato Tablet Specification

Requires Prescription (YES/NO)

Yes

Generics

Nitazoxanide

Used For

Diarrhoea

How it works

The antiprotozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic energy metabolism. Studies have shown that the PFOR enzyme from Giardia lamblia directly reduces nitazoxanide by transfer of electrons in the absence of ferredoxin. The DNA-derived PFOR protein sequence of Cryptosporidium parvum appears to be similar to that of Giardia lamblia. Interference with the PFOR enzyme-dependent electron transfer reaction may not be the only pathway by which nitazoxanide exhibits antiprotozoal activity.

Izato Tablet Usage And Safety

Dosage

Nitazoxanide

Side Effects

Body as a Whole: Asthenia, fever, pain, allergic reaction, pelvic pain, back pain, chills, chills and fever, flu syndrome. Nervous System: dizziness, somnolence, insomnia, tremor, hypesthesia. Digestive System: vomiting, dyspepsia, anorexia, flatulence, constipation, dry mouth, thirst. Urogenital System: discolored urine, dysuria, amenorrhea, metrorrhagia, kidney pain, edema labia. Metabolic & Nutrition: Increased SGPT. Hemic & Lymphatic Systems: anemia, leukocytosis. Skin: rash, pruritus. Special Senses: eye discoloration, ear ache. Respiratory System: epistaxis, lung disease, pharyngitis. Cardiovascular System: tachycardia, syncope, hypertension. Muscular System: myalgia, leg cramps, spontaneous bone fracture.

Drug Interactions

Warfarin

Indication

It is indicated for the treatment of diarrhea caused by Giardia lamblia or Cryptosporidium parvum.

When not to Use

It is contraindicated in patients with a prior hypersensitivity to nitazoxanide or any other ingredient in the formulations.

Izato Tablet Precautions

Precaution

The pharmacokinetics of nitazoxanide in patients with compromised renal or hepatic function have not been studied. Therefore, nitazoxanide must be administered with caution to patients with hepatic and biliary disease, to patients with renal disease and to patients with combined renal and hepatic disease.

Izato Tablet Warnings

Warning 1

Nitazoxanide Tablets and Nitazoxanide Oral Suspension should be taken with food.

Warning 2

Nitazoxanide Tablets and Nitazoxanide Oral Suspension have not been studied for the treatment of diarrhea caused by Giardia lamblia in HIV-infected or immunodeficient patients.

Warning 3

Information on nitazoxanide overdosage is not available. In the event of overdose, gastric lavage may be appropriate soon after dry administration. Patients should be carefully observed and given symptomatic and supportive treatment.

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