Mitzap Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Mirtazapine
Used For
Depression
How it works
Mirtazapine is a centrally active presynaptic a2 -antagonist, which increases central noradrenergic and serotonergic neurotransmission. The enhancement of serotonergic neurotransmission is specifically mediated via 5-HT1 receptors, because 5-HT2 and 5-HT3 receptors are blocked by Mirtazapine. The histamine H1-antagonistic activity of Mirtazapine is associated with its sedative properties.
Mitzap Tablets Usage And Safety
Dosage
Mirtazapine
Side Effects
Bone marrow depression (granulocytope-nia, agranulo-cytosis, aplastic anaemia, thrombo-cytopenia) , Eosinophilia , Weight increased , Increase in appetite Abnormal dreams , Confusion , Anxiety , Insomnia , Nightmares , Mania , Agitation , Hallucinations , Psychomotor restlessness (incl. akathisia, hyperkinesia) , Aggression , Suicidal ideation , Suicidal behaviour , Somnolence Sedation , Headache , Lethargy , Dizziness , Tremor , Paraesthesia , Restless legs, Syncope, Myoclonus , Convulsions (insults) , Serotonin syndrome , Oral paresthaesia , Dysarthria.
Drug Interactions
MAO inhibitors , SSRIs , benzodiazepines and other sedatives (notably most antipsychotics, histamine H1 antagonists, opioids , alcohol.
Indication
Treatment of episodes of major depression in adults.
When not to Use
• Hypersensitivity to the active substance • Concomitant use of Mirtazapine with monoamine oxidase (MAO) inhibitors.
Mitzap Tablets Precautions
Precaution
Mirtazapine should not be used in the treatment of children and adolescents under the age of 18 years. Suicide-related behaviors (suicide attempt and suicidal thoughts), and hostility (predominantly aggression, oppositional behavior and anger) may occur among children and adolescents treated with antidepressants.
Mitzap Tablets Warnings
Warning 1
The patient should be carefully monitored for the appearance of suicidal symptoms.
Warning 2
Bone marrow depression, usually presenting as granulocytopenia or agranulocytosis, may occur rarely during treatment with Mirtazapine.
Warning 3
Treatment should be discontinued if jaundice occurs.
Mitzap Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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