
SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Tobramycin
Used For
Bacterial Infection
How it works
Tobramycin is a potent, broad-spectrum, rapid working bactericidal aminoglycoside antibiotic. It exerts its primary effect on bacterial cells by inhibiting polypeptide assembly and synthesis on the ribosome.
USAGE AND SAFETY
Dosage
Tobramycin
Side Effects
• Eye irritation or feeling of having something in the eye • Inflammation of the cornea (clear front portion of your eye) (punctate keratitis) • Swollen / itchy eyelids • Eye redness • Increased tearing • skin rash • swelling of the face, hands or feet • wheezing, difficulty in breathing, shortness of breath • severe and sudden onset of pinkish, itchy swellings on the skin, also called hives or nettlerash • loss of eyelashes • lightening of skin.
Drug Interactions
• Beta lactam type antibiotics that are used to treat infections of the eye, ear or the skin• Medicines that can lead to hearing loss• Other aminoglycoside antibiotics that are similar to tobramycin
Indication
It is used to treat bacterial infections of the external part of the eye.
When not to Use
Do not use this medicine if you have an allergy to: • Tobramycin or other aminoglycoside antibiotics. • Any of the ingredients in the list.
PRECAUTIONS
Precaution
Prescribing tobramycin injection in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of development of drug-resistant bacteria.
WARNINGS
Warning 1
Patients treated with tobramycin injection and other aminoglycosides should be under close clinical observation, because these drugs have an inherent potential for causing ototoxicity and nephrotoxicity.
Warning 2
Tobramycin injection should be used with caution in premature and neonatal infants because of their renal immaturity and the resulting prolongation of serum half-life of the drug .
Warning 3
Concurrent and sequential use of other neurotoxic and/or nephrotoxic antibiotics, particularly other aminoglycosides (e.g., amikacin, streptomycin, neomycin, kanamycin, gentamicin, and paromomycin), cephaloridine, viomycin, polymyxin B, colistin, cisplatin, and vancomycin, should be avoided. Other factors that may increase patient risk are advanced age and dehydration.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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