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      Dvago

      Novoteph Capsules 40Mg

      Brand : sami pharm (pvt) ltd.

      Rs. 422.80

      Rs. 445.00

      |

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      SPECIFICATION

      Requires Prescription (YES/NO)

      Yes

      Generics

      Esomeprazole

      Used For

      Acidity & Ulcers

      How it works

      Esomeprazole works by binding irreversibly to the H+/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH .

      USAGE AND SAFETY

      Dosage

      Esomeprazole

      Side Effects

      Headache , GI upset , Skin reactions , Dry mouth. Rarely angioedema . Rarely angiooedema , anaphylaxis , fundic gland polyps.

      Drug Interactions

      Phenytoin , warfarin , clopidogrel , ketoconazole , itraconazole , voriconazole , diazepam , citalopram , imipramine , clomipramine , CYP3A4 inhibitors or inducers , tacrolimus , digoxin , erlitinib , methotraxate

      Indication

      Treatment of Heartburn , GERD , Gastritis & Ulcer

      When not to Use

      It is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions e.g. angioedema and anaphylaxis, bronchospasm, acute interstitial nephritis and urticaria have been reported with esomeprazole use.

      PRECAUTIONS

      Precaution

      Daily long-term use (e.g. longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.

      WARNINGS

      Warning 1

      Hypomagnesemia has been reported rarely with prolonged treatment with PPIs.

      Warning 2

      Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine.

      Warning 3

      Avoid concomitant use of Esomeprazole with clopidogrel.

      ADDITIONAL INFORMATION

      Pregnancy category

      Always consult your physician before using any medicine.

      Storage (YES/NO)

      Store this medicine at room temperature, away from direct light and heat.

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