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      pramcit tablets 20mg (1 box = 2 strips) (1 strip = 10 tablets) Product Image

      Pramcit Tablets 20Mg (1 Box = 2 Strips) (1 Strip = 10 Tablets)

      Rs. 570.00

      Rs. 600.00

      |

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      Pramcit Tablets Specification

      Requires Prescription (YES/NO)

      Yes

      Generics

      Citalopram HBr

      Used For

      Depression

      How it works

      The mechanism of action of citalopram HBr as an antidepressant is presumed to be linked to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT). In vitro and in vivo studies in animals suggest that citalopram is a highly selective serotonin reuptake inhibitor (SSRI) with minimal effects on norepinephrine (NE) and dopamine (DA) neuronal reuptake. Tolerance to the inhibition of 5-HT uptake is not induced by long-term (14-day) treatment of rats with citalopram. Citalopram is a racemic mixture (50/50), and the inhibition of 5-HT reuptake by citalopram is primarily due to the (S)-enantiomer.

      Pramcit Tablets Usage And Safety

      Dosage

      Citalopram HBr

      Side Effects

      GI upset , tremor , somnolence , dry mouth , anorexia , agitation , decreased lipid , anxiety , confusion , sleep disorders , tinnitus , yawning , pruritis , impotence , amnesia , apathy , increases salivation , increased sweating , abnormal accommodation. Hyponatraemia , bleeding disorders , serotonin syndrome .

      Drug Interactions

      MAOIs, lithium , tryptophan , pimozide , other neuroleptics , St.John's wort, other SSRIs , SNRIs , 5HT1 agonists , triptans , other serotonergic drugs , linezolid , drugs that prolong QT interval , tramadol , anticoagulants , NSAIDs and other drugs affecting plastelet function . CYP2D6 substrates (e.g., metoprolol) , CYP2C19 inhibitors (e.g. PPIs) , cimetidine , drugs that reduce seizure threshold . Drugs that induce hypokalaemia or hypomagnesaemia. Alcohol.

      Indication

      It is used in depressive disorders (endogenous and non-endogenous).

      When not to Use

      Hyersensitive to any of the ingredients.

      Pramcit Tablets Precautions

      Precaution

      All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases.

      Pramcit Tablets Warnings

      Warning 1

      Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of this medicine or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need.

      Warning 2

      Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior.

      Warning 3

      Families and caregivers should be advised of the need for close observation and communication with the prescriber. It is not approved for use in pediatric patients.

      Pramcit Tablets Additional Information

      Pregnancy category

      Always consult your physician before using any medicine.

      Storage (YES/NO)

      Store this medicine at room temperature, away from direct light and heat.

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