Description : CALCIUM : Calcium is the most abundant mineral in the body. Most individuals do not meet the daily requirement of Calcium.VITAMIN K2 : Vitamin K2 is necessary to convert a critical bone-building protein called osteocalcin. Inadequate K2 inhibits osteocalcin production and reduces calcium flow into bone tissue. This leads to reduced bone mass and a weakened bone matrix.D3 AND K2 FOR HEALTHY CALCIUM METABOLISM : Vitamin D3 is another critical nutrient that plays an essential role in calcium uptake into skeletal bone tissue. Several studies show that this combination enhanced osteocalcin accumulation in bone cells greater than any one of these nutrients alone. This increased osteocalcin formation significantly improved bone mineral density.Vitamin K2 and vitamin D3 work to increase Matrix GLA protein (MGP). This protein protects the blood vessels from calcification by congregating around the elastic fibers of the arterial lining and guarding against calcium crystal deposition.CARDIOVASCULAR AND JOINT HEALTH:Vitamin K2 and Vitamin D3 also play a very important role in cardiovascular and joint health. When soft tissues such as the arterioles are damaged due to oxidative stress the body responds with an inflammatory process. This process results in a deposition of calcium into the damaged tissues. This creates plaque buildup in arterioles and degenerative bone spurs in joints.CALCIUM INTAKE AND BONE MASS IN PREMENOPAUSAL WOMEN : Calcium Supplementation to a total calcium intake from 1200 to 2500 mg/day produces an annual mean percentage difference in bone mass of 1.6% at multiple skeletal sites.