Velosef 1G Injection 1Vial
Brand : glaxo smith kline pakistan
Per pc
Rs. 360.53
Rs. 379.50
How it works
Cephradine inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillinbinding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death.
Description
VELOSEF INJ 1 GM 1 VIAL
Generics
Cephradine
used for
Bacterial Infection
Requires Prescription (YES/NO)
Yes
Indication
Cephradine is indicated in the treatment of following infections:Upper respiratory tract infections: Sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis and otitis media.Lower respiratory tract infections: Acute and chronic bronchitis, lobar and bronchopneumonia.Skin and soft tissue infections: Impetigo, abscess, cellulitis and furunculosis. Urinary tract infections: Cystitis, urethritis and pyelonephritis.Gastrointestinal tract infections: Bacillary dysentery, enteritis and peritonitis
Side Effects
Gastrointestinal: Glossitis, nausea, vomiting, diarrhea or loose stools, tenesmus, abdominal paincolitis and pseudomembranous colitis. Hypersensitivity: Mild urticaria or skin rash, edema, erythema, pruritis, joint pain and drug fever. Hematologic: Mild, transient eosinophilia, leukpenia and neutropenia. Other: Headache, dizziness, dyspnea, paresthesia, candidal overgrowth and vaginitis.
When not to Use
Cephradine is contraindicated in patients with known hypersensitivity to cephradine or to any excipient of the product.
Dosage
Adult : The usual daily dosage of Cephradine Injection is 2 to 4g daily in four equally divided doses intramuscularly or intravenously . Pediatrics The usual dose range is 50 to 100mg/kg/day in equally divided doses four times a day and should be regulated by age, weight of the patient and severity of the infection being treated. The maximum pediatric daily dose should not exceed the dose recommended for adults. Always consult your doctor or pharmacist for dose adjustments.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Precautions
Cephradine should be used with caution in patients with known hypersensitivity to penicillins because of partial allergenicity between penicillins and the cephalosporins .
Warning 1
Caution should be exercised in patients with renal failure and dosage should be reduced.
Warning 2
False positive reaction for glucose in the urine may occur with Benedict's or Fehling's solution or with reagent tablets such as Clinitest following administration of cephradine.
Warning 3
Prolonged use with antibiotics may result in overgrowth of non susceptible microorganisms.
Pregnancy category
Always consult your physician before using any medicine.
Drug Interactions
Loop diuretics , probenecid , aminoglycosides , anticoagulants.
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