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vlep tablets 500mg (1 box = 1 strip)(1 strip = 10 tablets) Product Image

Vlep Tablets 500Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)

Rs. 0.00

Rs. 0.00

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Vlep Tablets Specification

Requires Prescription (YES/NO)

Yes

Generics

Vigabatrin

Used For

Epilepsy

How it works

The precise mechanism of Vigabatrin’s anti-seizure effect is unknown, but it is believed to be the result of its action as an irreversible inhibitor of ?-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the metabolism of the inhibitory neurotransmitter GABA. This action results in increased levels of GABA in the central nervous system .

Vlep Tablets Usage And Safety

Dosage

Vigabatrin

Side Effects

ADVERSE REACTIONS: The following are the adverse reactions: Magnetic Resonance Imaging (MRI) abnormalities in Infants, neurotoxicity, suicidal behavior and Ideation, withdrawal of Antiepileptic Drugs (AEDs), anemia, somnolence and fatigue, peripheral neuropathy, weight gain, edema, birth defects, deafness, delayed puberty, gastrointestinal hemorrhage, esophagitis, developmental delay, facial edema, malignant hyperthermia, multi-organ failure, cholestasis, dystonia, encephalopathy, hypertonia, hypotonia, muscle spasticity, myoclonus, optic neuritis, Acute psychosis, apathy, delirium, hypomania, neonatal agitation, psychotic disorder, Laryngeal edema, pulmonary embolism, respiratory failure, stridor, Angioedema, maculo-papular rash, pruritus, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN ) .

Drug Interactions

Phenytoin , Clonazepam , Other AEDs , Alcohol , Oral Contraceptives . Drug-Laboratory Test Interactions it decreases alanine transaminase (ALT) and aspartate transaminase (AST) plasma activity in up to 90% of patients. It may increase the amount of amino acids in the urine, possibly leading to a false positive test for certain rare genetic metabolic diseases (e.g., alpha aminoadipic aciduria).

Indication

Refractory Complex Partial Seizures (CPS) it is indicated as adjunctive therapy for adults and pediatric patients 10 years of age and older with refractory complex partial seizures. It is not indicated as a first line agent for complex partial seizures. Infantile Spasms (IS): It is indicated as monotherapy for pediatric patients with infantile spasms 1 month to 2 years of age.

When not to Use

None

Vlep Tablets Precautions

Precaution

Missed Dose: Before starting to take this medicine , talk to your healthcare provider about what you or your child should do if a dose is missed.

Vlep Tablets Warnings

Warning 1

It decreases alanine transaminase (ALT) and aspartate transaminase (AST) plasma activity in up to 90% of patients. It may increase the amount of amino acids in the urine, possibly leading to a false positive test for certain rare genetic metabolic diseases (e.g., alpha aminoadipic aciduria).

Warning 2

It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Warning 3

Management of Overdosage: There is no specific antidote for its overdose. Standard measures to remove unabsorbed drug should be used, including Body Weight [kg] 25 to 60 Total Daily Starting Dose [mg/day] 500 Total Daily Maintenance Dose [mg/day] 2000 elimination by emesis or gastric lavage. Supportive measures should be employed, including monitoring of vital signs and observation of the clinical status of the patient.

Vlep Tablets Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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