Nexum 40Mg Capsules 14S (Pack Size 2 X 7S)
Brand : getz pharma pakistan
How it works
Esomeprazole works by binding irreversibly to the H+/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH .
NEXUM CAP 40 MG 2X7'S
Acidity & Ulcers
Requires Prescription (YES/NO)
Treatment of Heartburn , GERD , Gastritis & Ulcer
Headache , GI upset , Skin reactions , Dry mouth. Rarely angioedema . Rarely angiooedema , anaphylaxis , fundic gland polyps.
When not to Use
It is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions e.g. angioedema and anaphylaxis, bronchospasm, acute interstitial nephritis and urticaria have been reported with esomeprazole use.
Adults : GERD : For Adults : 20mg or 40mg once daily for 4 to 8 weeks. 12 to 17 years -- 20mg or 40mg once dailly for upto 8 weeks. Gastric Ulcers : 20mg or 40mg once daily for upto 6 months . Erosive oesophagitis : 40mg once daily for 4-8 wk . Prevention of relapse , 20mg once daily . Children : Not recommended . OR As directed by your physician .
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Daily long-term use (e.g. longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
Hypomagnesemia has been reported rarely with prolonged treatment with PPIs.
Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine.
Avoid concomitant use of Esomeprazole with clopidogrel.
Always consult your physician before using any medicine.
Phenytoin , warfarin , clopidogrel , ketoconazole , itraconazole , voriconazole , diazepam , citalopram , imipramine , clomipramine , CYP3A4 inhibitors or inducers , tacrolimus , digoxin , erlitinib , methotraxate
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