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    Dvago

    Qmetem Plus Ds 80/480Mg Tablets 6S

    Rs. 361.02

    Rs. 380.00

    |

    QUICK DELIVERY

    SPECIFICATION

    Requires Prescription (YES/NO)

    Yes

    Generics

    Artemether , Lumefantrine

    Used For

    Malaria

    How it works

    Both components Artemether/ Lumefantrine have their own action site in the malarial parasite. The presence of the endoperoxide bridge in Artemether (generating single oxygen and free radicals, those are very cytotoxic to the plasmodia) appears to be essential for antimalarial activity.

    USAGE AND SAFETY

    Dosage

    Artemether , Lumefantrine

    Side Effects

    Very Common: Palpitations, headache, dizziness, abdominal pain, anorexia, vomiting, nausea, arthralgia, mylagia, asthenia, fatigue, sleep disorders.Common: Amnesia, paraesthesia, diarrhea, pruritus, rash, cough, electrocardiogram QT prolongation, gait disturbances, insomia.Uncommon: Liver function test increased, clonus, hypoesthesia, ataxia, somnolence.

    Drug Interactions

    CYP3A4 inhibitors (e.g. erythromycin, ketoconazole, itraconazole, cimetidine, HIV protease inhibitors, etc.) , CYP2D6 inhibitors (e.g. flecainide, metoprolol, imipramine, amitryptyline, clomipramine, etc.) , Mefloquine.

    Indication

    Used in the treatment of Malaria.

    When not to Use

    It is contraindicated to those patients which have a history of hypersensitivity to Artemether / Lumefantrine.

    PRECAUTIONS

    Precaution

    Due to limited data on safety and efficacy, Artemether+Lumefantrine should not be given concurrently with any other anti-malarial agent unless there is no other treatment option.

    WARNINGS

    Warning 1

    Caution is advised when administering Artemether + Lumefantrine to patients with severe renal, hepatic or cardiac problems. In such cases, monitoring of the ECG is recommended and steps should be taken to correct any electrolyte disturbances.

    Warning 2

    Caution is recommended when combining Artemether + Lumefantrine with drugs exhibiting variable patterns of inhibition, induction or competition for CYP3A4 as the therapeutic effects of some drugs could be altered.

    Warning 3

    Patients who remain averse to food during treatment should be closely monitored as the risk of recrudescence may be greater.

    ADDITIONAL INFORMATION

    Pregnancy category

    Always consult your physician before using any medicine.

    Storage (YES/NO)

    Store this medicine at room temperature, away from direct light and heat.

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