Salmicort Hfa 25/250Mcg Inhaler 1S
Brand : macter international
How it works
Salmeterol: Salmeterol is a selective long-acting (12 hour) ß2 adrenoceptor agonist with a long side chain which binds to the exo-site of the receptor. The pharmacologic effects of ß2 adrenoceptor agonist drugs, including salmeterol, are at least in part attributable to stimulation of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3’,5’-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. Fluticasone propionate: Fluticasone propionate given by inhalation atrecommendeddoses has a glucocorticoid anti-inflammatory action within the lungs, resulting in reduced symptoms and exacerbations of asthma, with less adverse effects than when corticosteroids are administered systemically .
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