Treatan 16Mg Tablets 28S (Pack Size 2 X 14S)
Brand : pharmevo (private) limited.
How it works
Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II). Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects thatinclude vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Candesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is, therefore, independent of the pathways for angiotensin II synthesis.
TREATAN TAB 16 MG 28'S
Requires Prescription (YES/NO)
Candesartan cilexetil is indicated for the treatment of hypertension in adults and children 1 to < 17 years of age. It may be used alone or in combination with other antihypertensive agents .
Body as a Whole: asthenia, fever.Central and Peripheral Nervous System: paresthesia, vertigo.Gastrointestinal System Disorder: dyspepsia, gastroenteritis.Heart Rate and Rhythm Disorders: tachycardia, palpitation.Metabolic and Nutritional Disorders: creatine phosphokinase increased, hyperglycemia, hypertriglyceridemia, hyperuricemia.Musculoskeletal System Disorders: myalgia.Platelet/Bleeding-Clotting Disorders: epistaxis.Ps ychiatric Disorders : anxiety, depres sion, somnolence.Respiratory System Disorders: dyspnea.Skin and Appendages Disorders: rash, increased sweating.Urinary System Disorders: hematuria.
When not to Use
Candesartan cilexetil is contraindicated in patients who are hypersensitive to this drug or any component of this product.
Hypertension : Adults : Dosage must be individualized. Response is dose related over the range of 2 to 32 mg. The usual recommended starting dose of Candesartan cilexetil is 16 mg once daily when it is used as monotherapy in patients who are not volume depleted. Candesartan cilexetil can be administered once or twice daily with total daily doses ranging from 8 mg to 32 mg. Most of the antihypertensive effect is present within 2 weeks, and maximal blood pressure reduction is generally obtained within 4 to 6 weeks of treatment with Candesartan ci lexetil . Candesartan cilexetil may be administered with or without food. Children 1 to <6 years of age: The dose range is 0.05 to 0.4 mg/kg per day. The recommended starting dose is 0.20 mg/kg.Children 6 to <17 years of age: For those less than 50 kg, the dose range is 2 to 16 mg per day. The recommended starting dose is 4 to 8 mg. For those greater than 50 kg, the dose range is 4 to 32 mg per day. Therecommended starting dose is 8 to 16 mg.An antihypertensive effect is usually present within 2 weeks, with full effect generally obtained within 4 weeks of treatment with Candesartan cilexetil.Children < 1 year of age must not receive Candesartan cilexetil for hypertension. OR As directed by your physician .
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
As with any antihypertensive agent, excessive blood pressure decrease in patients with ischaemic cardiopathy or ischaemic cerebrovascular disease could result in a myocardial infarction or stroke.
Hypotension may occur during treatment with candesartan in heart failure patients. It may also occur in hypertensive patients with intravascular volume depletion. Caution should be observed when initiating therapy and correction of hypovolaemia should be attempted.
Candesarten may increase blood urea and serum creatinine in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney.
During dialysis the blood pressure may be particularly sensitive to AT1- receptor blockade as a result of reduced plasma volume and activation of the renin-angiotensin-aldosterone system. Therefore, candesartan should be carefully titrated with thorough monitoring of blood pressure in patients on haemodialysis.
Always consult your physician before using any medicine.
Glyburide, nifedipine, digoxin, warfarin, hydrochlorothiazide, and oral contraceptives , enalapril , potassium-sparing diuretics, potassium supplement , heparin .
syr bd 1cc insulin 6mm syringe 1s
disprin 300mg dispersible tablets 100s (pack size 10 x 10s)
panadol 500mg tablets 200s ( pack size 20x10s)