Gatacin Eye Specification
Requires Prescription (YES/NO)
Yes
Generics
Gatifloxacin
Used For
Eye Infection
How it works
Gatifloxacin is an 8-methoxyfluoroquinolone with a 3-methylpiperazinyl substituent at C7. The antibacterial action of gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription, and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. The mechanism of action of fluoroquinolones including gatifloxacin is different from that of aminoglycoside, macrolide, and tetracycline antibiotics. Therefore, gatifloxacin may be active against pathogens that are resistant to these antibiotics and these antibiotics may be active against pathogens that are resistant to gatifloxacin. There is no cross-resistance between gatifloxacin and the aforementioned classes of antibiotics. Cross-resistance has been observed between systemic gatifloxacin and some other fluoroquinolones.
Gatacin Eye Usage And Safety
Dosage
Gatifloxacin
Side Effects
Inflammation, bleeding or other disorders of the see-through layer covering the surface of the eye (conjunctiva) ; Inflammation of the surface of the eye (cornea) , red and painful eyes , watery eyes , eyelid swelling , decreased vision , eye irritation , eye discharge , dry eye , skin redness , headache , taste disturbances .
Drug Interactions
Always tell your healthcare professional if you are taking any other medicine. (This includes complementary or traditional medicines.)
Indication
It is an antibiotic ophthalmic solution and is used for the treatment of conjunctivitis caused by bacteria.
When not to Use
Do not use If you are hypersensitive (allergic) to gatifloxacin, other quinolones or to any of the components in this medication ; Do not use in infants under the age of one year.
Gatacin Eye Precautions
Precaution
Some patients receiving topical ophthalmic gatifloxacin experienced hypersensitivity reactions including anaphylactic reactions, angioedema (including pharyngeal, laryngeal, or facial edema), dyspnea, urticaria, and itching, even following a single dose. Rare cases of Stevens-Johnson Syndrome were reported in association with topical ophthalmic gatifloxacin use. If an allergic reaction to gatifloxacin occurs, discontinue the drug.
Gatacin Eye Warnings
Warning 1
Prolonged use of Gatifloxacin may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy. Whenever clinical judgment dictates, examine the patient with the aid of magnification, such as slit lamp biomicroscopy and where appropriate, fluorescein staining.
Warning 2
It is for topical ophthalmic use. Gatifloxacin may cause corneal endothelial cell injury if introduced directly into the anterior chamber of the eye.
Warning 3
Caution should be exercised in the use of benzalkonium chloride preserved topical medication over an extended period in patients with extensive ocular surface diseases.
Gatacin Eye Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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