Hart 12.5 Mg 10 Tablets
Brand : macter international
How it works
Carvedilol is a vasodilatory non-selective beta-blocker, which reduces the peripheral vascular resistance by selective alpha 1- receptor blockade and suppresses the renin-angiotensin system through non-selective beta-blockade. Plasma renin activity is reduced and fluid retention is rare.
HART TAB 12.5 MG 10'S
Requires Prescription (YES/NO)
It is used to treat angina (chest pain) and mild, moderate or severe heart failure. It is also used to treat high blood pressure (hypertension).
• Bronchitis, pneumonia, upper respiratory tract infection • Infections of the urinary tract • Low numbers of red blood cells • Increase in weight • Elevated cholesterol levels • Loss of control of blood sugar in people with diabetes • Depression, depressed mood • Visual disturbance • Reduced lacrimation, eye irritation • Slow heart rate • Oedema (swelling of the body or parts of the body), fluid overload, increased volume of blood in the body • Dizziness when standing up quickly • Problems with blood circulation (signs include cold hands and feet), hardening of the arteries (atherosclerosis) worsening of symptoms in patients with Raynaud’s disease (fingers or toes turn first bluish, then whitish, and then reddish together with pain) or claudication (pain in the legs which worsens when walking) • Asthma and breathing problems • Fluid accumulation in the lungs • Diarrhoea • Malaise, vomiting, stomach pains, indigestion • Pains (e.g. in the arms and legs) • Acute renal insufficiency and disturbances in renal function in patients with hardening of the arteries and/or impaired renal function • Difficulty in passing urine
When not to Use
Do not take : If you are allergic to carvedilol or any of the other ingredients of this medicine ; If you have been told you have very severe heart failure and you have fluid retention (swelling) which is being treated with injections of medicines into your veins (intravenously); If you have liver disease; If you have impaired conduction of the heart (or heart block) .
High blood pressure : Adults: The usual starting dose is 12.5 mg once a day for the first two days. After this, the dose is increased to 25 mg once a day. If necessary, your doctor may gradually increase the dose further at intervals of two weeks or more. The maximum recommended daily dose is 50 mg (the maximum recommended single dose is 25 mg). Angina : Adults: The usual starting dose is 12.5 mg twice a day for the first two days. After this, the dose is increased to 25 mg twice a day. If necessary, your doctor may gradually increase the dose further at intervals of two weeks or more to a maximum of 100 mg a day in two doses . Heart Failure : The starting dose is 3.125 mg twice a day for two weeks. Your doctor will then gradually increase the strength of tablets you take at intervals of two weeks or more until you receive the dose that suits you best.
Storage yes or /no
Store this medicine at room temperature, away from direct light and heat.
Patients with a chronic obstructive pulmonary disease with a tendency towards bronchospasms who are not treated with oral or inhalation medicine should only be given carvedilol if the expected improvement outweighs the possible risk. Patients should be monitored closely in the initial phase, and titration of carvedilol and carvedilol dose should be reduced in case of bronchospasms.
Carvedilol may cause bradycardia. If there is a decrease in pulse rate to less than 55 beats per minute, and symptoms associated with bradycardia occur, the carvedilol dose should be reduced.
When carvedilol is used concomitantly with calcium channel blocking agents such as verapamil and diltiazem or with other antiarrhythmics, specifically amiodarone, the patient's blood pressure and ECG have to be monitored. Intravenous co-administration should be avoided .
Care should be taken in administrating carvedilol to patients with a history of serious hypersensitivity reactions and in those undergoing desensitisation therapy as beta-blockers may increase both the sensitivity towards allergens and the seriousness of anaphylactic reactions. Cautions should be exercised when prescribing beta-blockers to patients with psoriasis since skin reactions may be aggravated.
Always consult your physician before using any medicine.
Diltiazem, verapamil or amiodarone , isosorbide mononitrate or glyceryl trinitrate , Digoxin , doxazosin, reserpine, amlodipine or indoramin , fluoxetine, tricyclic antidepressants, barbiturates, phenothiazines, haloperidol or monoamine oxide inhibitors (MAOIs) , ciclosporin , clonidine or ergotamine , ibuprofen or diclofenac , estrogens , prednisolone , rifampicin or erythromycin , cimetidine , ketoconazole , ephedrine or pseudoephedrine .
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