SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Thalidomide
Used For
Cancer
How it works
Thalidomide works by helping the body’s immune system and directly attacking the cancer. It works in a number of different ways: By stopping the cancer cells developing ; By stopping blood vessels growing in the cancer ; By stimulating part of the immune system to attack the cancer cells .
USAGE AND SAFETY
Dosage
Thalidomide
Side Effects
Somnolence , headache , rash , impotency , dizziness , diarrhoea , leukopenia , anemia , peripheral neuropathy , tremor, dizziness , syncope , paraesthesia , dysaesthesia , abnormal coordination , cardiac failure , bradycardia , pulmonary embolism , interstitial lung disease , skin reaction , oedema , fever , asthenia , fatigue , confusion , depression , blood dyscrasias, reports of hepatic disorders.
Drug Interactions
Anxiolytics, hypnotics, antipsychotics, H1 antihistamines, opiate derivatives, barbiturates and alcohol , vincristine and bortezomib , Warfarin , Digoxin.
Indication
It is used with two other medicines called ‘melphalan’ and ‘prednisone’ to treat adults with a type of cancer called multiple myeloma .
When not to Use
Hypersensitive to any of the ingredients in the list.
PRECAUTIONS
Precaution
Myocardial infarction (MI) has been reported in patients receiving thalidomide, particularly in those with known risk factors. Patients with known risk factors for MI, including prior thrombosis, should be closely monitored and action should be taken to try to minimise all modifiable risk factors (e.g. smoking, hypertension, and hyperlipidaemia).
WARNINGS
Warning 1
Thalidomide is a powerful human teratogen, inducing a high frequency of severe and life-threatening birth defects. Thalidomide must never be used by women who are pregnant or by women who could become pregnant unless all the conditions of the Pregnancy Prevention Programme are met.
Warning 2
Patients should be instructed never to give this medicinal product to another person and to return any unused capsules to their pharmacist at the end of treatment.
Warning 3
Patients should not donate blood during treatment (including during dose interruptions) and for at least 7 days following discontinuation of thalidomide.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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