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    Dvago

    Paroxin-Cr 12.5Mg Tablets 30S (Pack Size 3 X 10S)

    Rs. 741.00

    Rs. 780.00

    |

    QUICK DELIVERY

    SPECIFICATION

    Requires Prescription (YES/NO)

    Yes

    Generics

    Paroxetine HCl

    Used For

    Depression

    How it works

    The efficacy of paroxetine in the treatment of major depressive disorder, social anxiety disorder, obsessive compulsive disorder (OCD), panic disorder (PD), generalized anxiety disorder (GAD), and posttraumatic stress disorder (PTSD) is presumed to be linked to potentiation of serotonergic activity in the central nervous system resulting from inhibition of neuronal reuptake of serotonin (5-hydroxy-tryptamine, 5-HT).

    USAGE AND SAFETY

    Dosage

    Paroxetine HCl

    Side Effects

    Abnormal bleeding, predominantly of the skin and mucous membranes (mostly ecchymosis), thrombocytopenia , allergic reactions (including urticaria and angioedema , syndrome of inappropriate anti-diuretic hormone secretion (SIADH) , hyponatraemia , somnolence, insomnia, agitation, abnormal dreams (including nightmares) , confusion, hallucinations , dizziness, tremor, headache.

    Drug Interactions

    L-tryptophan, triptans, tramadol, SSRIs, lithium, fentanyl and St. John’s Wort – Hypericum perforatum – preparations , Pimozide , carbamazepine, rifampicin, phenobarbital, phenytoin , Fosamprenavir , ritonavir , Procyclidine , carbamazepine, phenytoin, sodium valproate , tricyclic antidepressants, phenothiazine neuroleptics, risperidone, atomoxetine, certain Type 1c antiarrhythmics and metoprolol.

    Indication

    It is indicated for the symptomatic relief of Major Depressive Disorder.

    When not to Use

    Known hypersensitivity to paroxetine and excepients. Paroxetine should not be used in combination with monoamine oxidase (MAO) inhibitors (including linezolid, an antibiotic which is a reversible non-selective MAO inhibitor) or within 2 weeks of terminating treatment with MAO inhibitors. Likewise, MAO inhibitors should not be introduced within 2 weeks of cessation of therapy with paroxetine.

    PRECAUTIONS

    Precaution

    Treatment with antidepressants is associated with an increased risk of suicidal thinking and behaviour in children and adolescents with Major Depressive Disorder (MDD) and other psychiatric disorders.

    WARNINGS

    Warning 1

    Epidemiological studies on bone fracture risk following exposure to some antidepressants, including SSRIs, have reported an association with fractures. The risk occurs during treatment and is greatest in the early stages of therapy. The possibility of fracture should be considered in the care of patients treated with paroxetine.

    Warning 2

    Caution is recommended in patients with severe renal impairment or in those with hepatic impairment.

    Warning 3

    Overall the incidence of seizures is less than 0.1% in patients treated with paroxetine. The drug should be discontinued in any patient who develops seizures.

    ADDITIONAL INFORMATION

    Pregnancy category

    Always consult your physician before using any medicine.

    Storage (YES/NO)

    Store this medicine at room temperature, away from direct light and heat.

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